Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MMP14 | P50281 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5066814 | 1.00 | TDP1 (0.38) | TDP1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL5116816 | 0.78 | ALDH1A1 (0.37) | TDP1ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL6690674 | 0.77 | NR4A2 (0.35) | ALDH1A1KDM4EMAPTMAPK1MEN1 | |
| SCHEMBL782083 | 0.77 | ALDH1A1 (0.37) | TDP1ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL5457433 | 0.76 | CRHBP (0.37) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL6676223 | 0.76 | CRHBP (0.40) | TDP1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL1651160 | 0.76 | PDPK1 (0.42) | TDP1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL30361763 | 0.76 | PDPK1 (0.42) | TDP1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL10953240 | 0.76 | AMY1A (0.35) | TDP1ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL14078775 | 0.76 | RAB9A (0.35) | ALDH1A1KDM4ENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901646-B | Benzotriazine bisoxides and pharmaceutical compositions thereof | 浙江瑞臻医药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114901646-A | Benzotriazine double oxide and pharmaceutical composition thereof | 杭州瑞臻医药有限公司 | 2022-08-12 | — | — | CN | disclosed |