Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | TDO2 | P48775 | 3/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28844709 | 0.89 | P2RX7 (0.47) | P2RX7IDO1TDO2GRM4MAPK14 | |
| SCHEMBL28844746 | 0.77 | IDO1 (0.76) | IDO1TDO2 | |
| SCHEMBL29865339 | 0.74 | IDO1 (0.61) | P2RX7IDO1TDO2TGFBR1 | |
| SCHEMBL28844660 | 0.74 | IDO1 (0.61) | P2RX7IDO1TDO2TGFBR1 | |
| SCHEMBL29864939 | 0.73 | IDO1 (0.59) | IDO1TDO2 | |
| SCHEMBL17429463 | 0.73 | RHEB (0.63) | P2RX7RHEB | |
| SCHEMBL28844711 | 0.72 | IDO1 (0.46) | P2RX7IDO1TDO2GRM4P2RY4 | |
| SCHEMBL28341117 | 0.70 | P2RX7 (0.47) | P2RX7IDO1TDO2 | |
| SCHEMBL28341101 | 0.69 | IDO1 (0.44) | P2RX7IDO1TDO2MAPK14TGFBR1 | |
| SCHEMBL1020747 | 0.68 | RHEB (0.50) | RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |