Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 0.46 |
| ▸ | TDO2 | P48775 | 15/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28338824 | 0.78 | IDO1 (0.44) | IDO1TDO2FBP1 | |
| Ethoxycarbonyl Group SCHEMBL28844709 | 0.78 | P2RX7 (0.47) | IDO1TDO2GRM4P2RY4P2RX7 | |
| SCHEMBL28338777 | 0.76 | IDO1 (0.43) | IDO1TDO2FBP1 | |
| SCHEMBL28844746 | 0.76 | IDO1 (0.76) | IDO1TDO2 | |
| SCHEMBL28880746 | 0.74 | PTGS2 (0.45) | IDO1TDO2 | |
| SCHEMBL29864939 | 0.74 | IDO1 (0.59) | IDO1TDO2FBP1 | |
| SCHEMBL29865098 | 0.72 | P2RX7 (0.51) | IDO1TDO2GRM4P2RY4P2RX7 | |
| SCHEMBL28168776 | 0.71 | FBP1 (0.48) | FBP1 | |
| SCHEMBL28678160 | 0.68 | MTNR1A (0.58) | IDO1 | |
| SCHEMBL27473001 | 0.68 | HRH4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |