Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.47 |
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
| ▸ | TDO2 | P48775 | 6/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865098 | 0.89 | P2RX7 (0.51) | P2RX7IDO1TDO2GRM4MAPK14 | |
| SCHEMBL28844711 | 0.78 | IDO1 (0.46) | P2RX7IDO1TDO2GRM4P2RY4 | |
| Ethoxycarbonyl Group SCHEMBL28338823 | 0.77 | P2RX7 (0.40) | P2RX7IDO1TDO2 | |
| Ethoxycarbonyl Group SCHEMBL28338776 | 0.77 | P2RX7 (0.44) | P2RX7IDO1TDO2 | |
| Ethoxycarbonyl Group SCHEMBL28880744 | 0.73 | JAK2 (0.48) | IDO1TDO2MAPK14 | |
| Ethoxycarbonyl Group SCHEMBL27309525 | 0.73 | RHEB (0.43) | P2RX7 | |
| SCHEMBL29864939 | 0.72 | IDO1 (0.59) | IDO1TDO2 | |
| Ethoxycarbonyl Group SCHEMBL28272556 | 0.71 | RHEB (0.41) | P2RX7 | |
| SCHEMBL28844746 | 0.70 | IDO1 (0.76) | IDO1TDO2 | |
| Ethoxycarbonyl Group SCHEMBL28168775 | 0.70 | MAPK14 (0.52) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |