Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | STK4 | Q13043 | 1/20 | 0.33 |
| ▸ | STK3 | Q13188 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25529250 | 0.89 | RIPK1 (0.36) | RIPK1PIK3CAPIK3CBPIK3CGSTK4 | |
| SCHEMBL30174220 | 0.81 | CSNK1E (0.38) | RIPK1RPS6KB1AKT1PIK3CAPIK3CB | |
| SCHEMBL30174263 | 0.79 | ALOX5 (0.39) | PIK3CAPIK3CBPIK3CGCSNK1ESTK4 | |
| SCHEMBL30174188 | 0.78 | TSHR (0.45) | RIPK1PIK3CAPIK3CBPIK3CGSTK4 | |
| SCHEMBL30174208 | 0.75 | PTGS2 (0.41) | CSNK1EMKNK1MKNK2PRKDC | |
| SCHEMBL30174219 | 0.75 | CSNK1E (0.34) | RIPK1RPS6KB1AKT1CSNK1EPIK3C3 | |
| SCHEMBL30174179 | 0.72 | HDAC1 (0.33) | CSNK1E | |
| SCHEMBL25529254 | 0.70 | RIPK1 (0.38) | RIPK1PIK3CAPIK3CBPIK3CGCSNK1E | |
| SCHEMBL29867907 | 0.69 | KDM4E (0.30) | — | |
| SCHEMBL25229526 | 0.68 | ALOX5 (0.42) | PIK3CAPIK3CBPIK3CGSTK4STK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |