SCHEMBL29869445

SCHEMBL29869445

O=P(O)(O)OC1[C@@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)C(OP(=O)(O)OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@H]1OP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ITPR3 Q14573 7/20 0.56
ITPR2 Q14571 3/20 0.54
ITPR1 Q14643 3/20 0.54
INPPL1 O15357 1/20 0.54
AKT1 P31749 1/20 0.54
SMPD1 P17405 1/20 0.52
INPP5A Q14642 3/20 0.48
FDPS P14324 1/20 0.45
BLM P54132 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6710149 1.00 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL3498450 1.00 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL29602097 1.00 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL30629453 1.00 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL6708568 1.00 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL3500008 1.00 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL613185 1.00 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL30713458 1.00 ITPR3 (0.56) ITPR3ITPR2ITPR1INPPL1AKT1
Scyllitol SCHEMBL5997336 0.91 ITPR3 (0.64) ITPR3ITPR2ITPR1INPPL1AKT1
SCHEMBL4343592 0.91 ITPR3 (0.74) ITPR3ITPR2ITPR1INPPL1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071221-A1 Fibroblast Growth Factor (FGF)21 Inhibition for Treatment of Cardiac Hypertrophy UNIVERSITY OF CINCINNATI (US) 2026-03-12 US disclosed
US-20250197875-A1 ENGINEERED PLANTS HAVING MODIFIED INOSITOL PYROPHOSPHATES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2025-06-19 US disclosed
US-20250154477-A1 NUDIX OVEREXPRESSING ENGINEERED PLANTS AND USES THEREOF VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2025-05-15 US disclosed
US-20240409928-A1 NOVEL RNA TRANSCRIPT PTC THERAPEUTICS, INC. 2024-12-12 US disclosed
WO-2023178098-A2 ENGINEERED PLANTS HAVING MODIFIED INOSITOL PYROPHOSPHATES VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) 2023-09-21 WO disclosed
WO-2023141501-A2 NUDIX OVEREXPRESSING ENGINEERED PLANTS AND USES THEREOF VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2023-07-27 WO disclosed
US-20230220018-A1 HETEROLOGOUS DDP1 EXPRESSING PLANTS AND USES THEREOF VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2023-07-13 US disclosed
CN-115161396-B Application of PPIP5K2 and compound thereof in regulating and controlling ovarian cancer progression 四川大学华西第二医院 2023-04-07 CN disclosed
CN-115232874-B Application of long-chain non-coding RNA in regulation and control of ovarian cancer progression 四川大学华西第二医院 2023-04-07 CN disclosed
CN-115232874-A Application of long-chain non-coding RNA in regulation and control of ovarian cancer progression 四川大学华西第二医院 2022-10-25 CN disclosed
CN-115161396-A Application of PPIP5K2 and compound thereof in regulating and controlling ovarian cancer progression 四川大学华西第二医院 2022-10-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071221-A1 Fibroblast Growth Factor (FGF)21 Inhibition for Treatment of Cardiac Hypertrophy FGF23, FGF1, FGF2 ITPR3 4501/4885ITPR2 4415/4885ITPR1 4330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.