SCHEMBL29869740

SCHEMBL29869740

COc1ccc(C(=O)c2ccc3cc(Br)ccc3c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.74
LMNA P02545 3/20 0.74
NPSR1 Q6W5P4 2/20 0.74
MAPK1 P28482 2/20 0.74
MEN1 O00255 1/20 0.74
RAB9A P51151 1/20 0.74
KMT2A Q03164 1/20 0.74
RXFP1 Q9HBX9 1/20 0.74
ALDH1A1 P00352 3/20 0.58
GAA P10253 1/20 0.58
HPGD P15428 2/20 0.54
KDM4E B2RXH2 1/20 0.53
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53
TUBA1B P68363 1/20 0.53
TUBA4A P68366 1/20 0.53
TUBB4B P68371 1/20 0.53
TUBB3 Q13509 1/20 0.53
TUBB2A Q13885 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21679446 1.00 MAPT (0.74) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL9718965 0.89 ALDH1A1 (0.70) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL18288074 0.86 KDM4E (0.70) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL29869689 0.86 MAPT (0.68) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL21679517 0.86 MAPT (0.68) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL1010096 0.86 RAB9A (1.00) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL3458301 0.83 LMNA (0.69) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL18288072 0.83 KDM4E (0.66) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL12276571 0.83 ALDH1A1 (0.62) MAPTLMNANPSR1MAPK1MEN1
SCHEMBL6557518 0.83 RAB9A (0.65) MAPTLMNANPSR1MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843853-B Composition and method for manufacturing device using the same 东洋合成工业株式会社 2022-09-20 CN disclosed