SCHEMBL9718965

SCHEMBL9718965

COc1ccc(C(=O)c2ccc3cc(C(=O)c4ccc(OC)cc4)ccc3c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.70
GAA P10253 1/20 0.70
MAPT P10636 3/20 0.66
LMNA P02545 2/20 0.66
MAPK1 P28482 2/20 0.66
HPGD P15428 2/20 0.66
NPSR1 Q6W5P4 2/20 0.66
RAB9A P51151 2/20 0.66
RXFP1 Q9HBX9 2/20 0.66
MEN1 O00255 1/20 0.66
KMT2A Q03164 1/20 0.66
KDM4E B2RXH2 1/20 0.63
TUBB4A P04350 1/20 0.62
TUBB P07437 1/20 0.62
TUBA3C P0DPH7 1/20 0.62
TUBA1B P68363 1/20 0.62
TUBA4A P68366 1/20 0.62
TUBB4B P68371 1/20 0.62
TUBB3 Q13509 1/20 0.62
TUBB2A Q13885 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18288074 0.96 KDM4E (0.70) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL8459975 0.93 KDM4E (0.77) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL6557518 0.93 RAB9A (0.65) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL12276571 0.93 ALDH1A1 (0.62) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL18288072 0.93 KDM4E (0.66) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL11810869 0.92 KDM4E (0.75) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL29869740 0.89 MAPT (0.74) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL21679446 0.89 MAPT (0.74) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL9418310 0.89 RXFP1 (0.79) ALDH1A1GAAMAPTLMNAMAPK1
SCHEMBL51509 0.89 RXFP1 (0.79) ALDH1A1GAAMAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018127-B2 Additive manufacturing of aromatic thermoplastics from photocurable precursor salts VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2024-06-25 US disclosed
US-12018127-B2 Additive manufacturing of aromatic thermoplastics from photocurable precursor salts VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2024-06-25 US disclosed
US-20200369831-A1 ADDITIVE MANUFACTURING OF AROMATIC THERMOPLASTICS FROM PHOTOCURABLE PRECURSOR SALTS VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2020-11-26 US disclosed
US-5126427-A For stable solutions in halogenated hydrocarbons, solvent resistance, thermal poroperties, molding materials, coatings CIBA-GEIGY CORPORATION (US) 1992-06-30 US disclosed
EP-0447358-A2 Soluble polyarylene ether sulfones CIBA-GEIGY AG (CH) 1991-09-18 EP disclosed