SCHEMBL29869998

SCHEMBL29869998

COc1ccc([C@@H]2COc3cc(O)ccc3C2)c(O)c1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.57
ESR1 P03372 1/20 0.57
ESR2 Q92731 1/20 0.57
ALOX15 P16050 4/20 0.56
ALOX12 P18054 4/20 0.56
PTPN1 P18031 5/20 0.48
TYR P14679 3/20 0.48
CYP3A4 P08684 2/20 0.48
NPC1 O15118 1/20 0.48
HSP90AA1 P07900 1/20 0.48
RAB9A P51151 1/20 0.48
ALOX15B O15296 2/20 0.46
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29114658 1.00 TTR (0.57) TTRESR1ESR2ALOX15ALOX12
SCHEMBL30205823 1.00 TTR (0.57) TTRESR1ESR2ALOX15ALOX12
SCHEMBL13829404 1.00 TTR (0.57) TTRESR1ESR2ALOX15ALOX12
SCHEMBL31643797 1.00 TTR (0.57) TTRESR1ESR2ALOX15ALOX12
SCHEMBL1850123 1.00 TTR (0.57) TTRESR1ESR2ALOX15ALOX12
SCHEMBL29369381 0.96 ALOX15 (0.55) TTRESR1ESR2ALOX15ALOX12
SCHEMBL29724948 0.95 ALOX15 (0.59) TTRESR1ESR2ALOX15ALOX12
SCHEMBL28770238 0.95 ALOX15 (0.59) TTRESR1ESR2ALOX15ALOX12
SCHEMBL31544871 0.90 TTR (0.54) TTRESR1ESR2ALOX15ALOX12
SCHEMBL29737518 0.90 TTR (0.54) TTRESR1ESR2ALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12257280-B2 Composition for preventing or treating muscular diseases, containing, as active ingredient, Glycyrrhiza uralensis extract or compound isolated therefrom NEO CREMAR CO., LTD. (KR) 2025-03-25 US disclosed
CN-118501289-A Red cone wood color breeding method 中国林业科学研究院热带林业实验中心 2024-08-16 CN disclosed
CN-117137902-B Application of (-) -equitable edible phenol in preparing medicine for preventing and/or treating Alzheimer disease 首都医科大学宣武医院 2024-05-07 CN disclosed
CN-112739362-B Composition for preventing or treating muscular disease comprising licorice extract or compound isolated therefrom as active ingredient 新可利玛股份有限公司 2022-08-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12257280-B2 Composition for preventing or treating muscular diseases, containing, as active ingredient, Glycyrrhiza uralensis extract or compound isolated therefrom PYGM, MUSK, GYS1 TTR 1656/4885ESR1 4693/4885ESR2 4140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.