Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | GALR3 | O60755 | 1/20 | 0.67 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | VDR | P11473 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425872 | 1.00 | RAB9A (0.67) | RAB9ANPC1GALR3NR2F2SMN1; SMN2 | |
| SCHEMBL7970556 | 0.80 | GALR3 (1.00) | RAB9ANPC1GALR3NR2F2SMN1; SMN2 | |
| SCHEMBL28427226 | 0.80 | TDP1 (0.60) | RAB9ANPC1GALR3NR2F2SMN1; SMN2 | |
| SCHEMBL29870465 | 0.80 | TDP1 (0.60) | RAB9ANPC1GALR3NR2F2SMN1; SMN2 | |
| SCHEMBL14398683 | 0.80 | ALDH1A1 (0.62) | RAB9ANPC1GALR3NR2F2SMN1; SMN2 | |
| SCHEMBL2084701 | 0.79 | VDR (0.72) | RAB9ANPC1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL7508470 | 0.79 | NPC1 (0.74) | RAB9ANPC1GALR3NR2F2SMN1; SMN2 | |
| SCHEMBL3616241 | 0.79 | KDM4E (0.65) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12768325 | 0.78 | NPC1 (0.72) | RAB9ANPC1GALR3NR2F2SMN1; SMN2 | |
| SCHEMBL10144719 | 0.76 | SMN1; SMN2 (1.00) | RAB9ANPC1GALR3NR2F2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393372-B | Benzimidazole derivative and preparation method and application thereof | 中国药科大学 | 2022-08-26 | — | — | CN | disclosed |