SCHEMBL2987249

SCHEMBL2987249

CC(NC(Cc1ccc(O)cc1)C(=O)O)c1ccccc1O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.51
MME P08473 8/20 0.51
ACE P12821 8/20 0.48
POLB P06746 1/20 0.48
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
CPA1 P15085 2/20 0.47
ACE2 Q9BYF1 2/20 0.47
NAALAD2 Q9Y3Q0 1/20 0.45
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2990815 0.93 POLB (0.55) MMEACEPOLBCPA1ACE2
SCHEMBL2976458 0.86 FOLH1 (0.51) FOLH1MMEACECPA1ACE2
SCHEMBL2982721 0.86 FOLH1 (0.51) FOLH1MMEACECPA1ACE2
SCHEMBL2984585 0.85 ACE (0.47) FOLH1MMEACECPA1ACE2
SCHEMBL2980632 0.85 NOS2 (0.47) FOLH1MMEACECPA1ACE2
SCHEMBL2982925 0.85 FOLH1 (0.52) FOLH1MMEACEMMP9MMP8
SCHEMBL16017459 0.85 MMP9 (0.60) FOLH1MMEACEMMP9MMP8
SCHEMBL2979320 0.84 NOS2 (0.46) FOLH1MMEACECPA1ACE2
SCHEMBL2985294 0.81 POLB (0.50) MMEPOLBTSHR
SCHEMBL2982927 0.80 POLB (0.49) MMEACEPOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US claimed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 FOLH1 2609/4885MME 1263/4885ACE 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.