Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21239547 | 1.00 | ALOX15 (0.40) | ALOX15GFERADAM17ALDH1A1DRD1 | |
| SCHEMBL25220639 | 0.85 | ALOX15 (0.38) | ALOX15GFERADAM17ALDH1A1DRD1 | |
| SCHEMBL9714369 | 0.83 | CETP (0.35) | ALDH1A1HPGDCYP3A4TDP1MAPT | |
| SCHEMBL9826232 | 0.82 | CYP3A4 (0.41) | ALOX15GFERADAM17ALDH1A1DRD1 | |
| SCHEMBL4056724 | 0.79 | CYP3A4 (0.50) | ALDH1A1MEN1KMT2AHPGDCYP3A4 | |
| SCHEMBL9489490 | 0.79 | ALDH1A1 (0.44) | ALOX15ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10591868 | 0.79 | LMNA (0.39) | ALDH1A1LMNAHPGDCYP3A4TDP1 | |
| SCHEMBL10592920 | 0.77 | ALDH1A1 (0.33) | ALDH1A1HPGDCYP3A4TDP1 | |
| SCHEMBL10589873 | 0.77 | PDE2A (0.33) | ALDH1A1HPGDCYP3A4TDP1 | |
| SCHEMBL10590570 | 0.76 | ALDH1A1 (0.34) | ALDH1A1HPGDCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843283-B | Urea derivatives | 第一三共株式会社 | 2022-08-30 | — | — | CN | disclosed |