Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29874044 | 0.82 | ALOX15 (0.40) | CYP3A4LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL21239547 | 0.82 | ALOX15 (0.40) | CYP3A4LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9826837 | 0.81 | CYP3A4 (0.41) | CYP3A4TRPA1ALDH1A1HPGDTDP1 | |
| SCHEMBL162798 | 0.80 | CYP3A4 (0.51) | CYP3A4TRPA1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10695518 | 0.79 | CYP3A4 (0.37) | CYP3A4TRPA1ALDH1A1HPGDTDP1 | |
| SCHEMBL10341831 | 0.77 | CYP3A4 (0.43) | CYP3A4TRPA1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8564350 | 0.77 | CYP3A4 (0.43) | CYP3A4TRPA1LMNAKMT2AMEN1 | |
| SCHEMBL10341987 | 0.75 | PDIA6 (0.47) | CYP3A4TRPA1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10038435 | 0.75 | CYP3A4 (0.42) | CYP3A4TRPA1ALDH1A1HPGDTDP1 | |
| SCHEMBL10392671 | 0.75 | CYP3A4 (0.42) | CYP3A4TRPA1ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316734-B1 | FURAZANYL UREAS | BAYER AG (DE) | 1991-07-03 | — | — | EP | disclosed |
| US-4886823-A | Furazanylurea acaricides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0316734-A2 | Furazanyl ureas | BAYER AG (DE) | 1989-05-24 | — | — | EP | disclosed |