Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 5/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18079795 | 0.89 | CES2 (0.54) | MTORCES2CES1HDAC1HDAC2 | |
| SCHEMBL15209694 | 0.87 | CES2 (0.61) | MTORCES2CES1HDAC1HDAC2 | |
| SCHEMBL28278184 | 0.84 | MTOR (0.40) | MTORCES2CES1HDAC1HDAC2 | |
| SCHEMBL7604854 | 0.84 | L3MBTL1 (0.56) | CES2CES1ATMTDP1L3MBTL1 | |
| SCHEMBL29532021 | 0.82 | CA12 (0.58) | MTORTDP1L3MBTL1CA12CA1 | |
| SCHEMBL40282 | 0.82 | CA12 (0.58) | MTORTDP1L3MBTL1CA12CA1 | |
| SCHEMBL30967896 | 0.81 | MGLL (0.42) | MTORCES2CES1HDAC1HDAC2 | |
| Methane SCHEMBL14879758 | 0.80 | CA12 (0.56) | MTORTDP1L3MBTL1CA12CA1 | |
| Hydrochloric Acid SCHEMBL4455397 | 0.80 | CA12 (0.56) | MTORTDP1L3MBTL1CA12CA1 | |
| SCHEMBL3673834 | 0.79 | ATM (0.58) | MTORHDAC1HDAC2GRM5F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |