Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29876164 | 0.81 | ADRA2A (0.55) | PTK2ADRA2AADRA2BADRA2CL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28891676 | 0.81 | ADRA2A (0.55) | PTK2ADRA2AADRA2BADRA2CL3MBTL1 | |
| SCHEMBL29875822 | 0.76 | KDM4E (0.38) | TNIKCHEK1 | |
| SCHEMBL28862861 | 0.71 | CHEK1 (0.51) | FYNTNIKCCNT1CDK4CCND1 | |
| SCHEMBL28891651 | 0.71 | SLC2A1 (0.54) | ADRA2AADRA2BADRA2CMAPKAPK2TNIK | |
| SCHEMBL11031045 | 0.70 | RAD52 (0.55) | PTK2RAD52MAPKAPK2FYNTNIK | |
| SCHEMBL28891629 | 0.69 | SLC2A1 (0.47) | ADRA2AADRA2BADRA2CTNIKBTK | |
| SCHEMBL4143075 | 0.69 | MAPKAPK2 (0.75) | ADRA2AADRA2BADRA2CRAD52MAPKAPK2 | |
| SCHEMBL11031445 | 0.68 | SLC2A1 (0.51) | PTK2RAD52MAPKAPK2BTKCCNT1 | |
| SCHEMBL11031861 | 0.67 | SLC2A1 (0.55) | ADRA2AADRA2BADRA2CMAPKAPK2TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197154-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2022-10-18 | — | — | CN | disclosed |