Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 4/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875994 | 0.92 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10TNIKLRRK2 | |
| SCHEMBL28891734 | 0.92 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10TNIKLRRK2 | |
| SCHEMBL28891616 | 0.80 | ADRA2A (0.41) | KDM4EALDH1A1WDR5KMT2ACLK4 | |
| SCHEMBL29875779 | 0.80 | ADRA2A (0.41) | KDM4EALDH1A1WDR5KMT2ACLK4 | |
| SCHEMBL28891739 | 0.79 | SLC2A1 (0.39) | KDM4EALDH1A1HTR1DMAPK14EML4 | |
| SCHEMBL28891628 | 0.77 | SLC2A1 (0.41) | CLK4TNIKLRRK2CHEK1EML4 | |
| SCHEMBL28891635 | 0.76 | SLC2A1 (0.41) | CLK4TNIKCHEK1EML4ALK | |
| Trifluoroacetic Acid SCHEMBL29875659 | 0.76 | PTK2 (0.44) | TNIKCHEK1 | |
| SCHEMBL29876463 | 0.72 | EML4 (0.47) | EML4ALK | |
| SCHEMBL28891852 | 0.72 | EML4 (0.47) | EML4ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197154-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2022-10-18 | — | — | CN | disclosed |