Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23214924 | 1.00 | GPR119 (0.44) | GPR119TRPV3STSMEN1KMT2A | |
| SCHEMBL23215172 | 0.90 | ALDH1A1 (0.42) | GPR119STSMEN1KMT2ANPSR1 | |
| SCHEMBL29886059 | 0.90 | ALDH1A1 (0.42) | GPR119STSMEN1KMT2ANPSR1 | |
| SCHEMBL29886795 | 0.89 | STS (0.42) | GPR119STSMEN1KMT2ANPSR1 | |
| SCHEMBL23216598 | 0.89 | LMNA (0.42) | GPR119STSMEN1KMT2ANPSR1 | |
| SCHEMBL23215013 | 0.89 | STS (0.42) | GPR119STSMEN1KMT2ANPSR1 | |
| SCHEMBL29886780 | 0.79 | LMNA (0.44) | MEN1KMT2ALMNASMN1; SMN2TACR3 | |
| SCHEMBL23216381 | 0.79 | LMNA (0.44) | MEN1KMT2ALMNASMN1; SMN2TACR3 | |
| SCHEMBL23216282 | 0.77 | PDK4 (0.43) | GPR119 | |
| SCHEMBL29886388 | 0.77 | PDK4 (0.43) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041407-A1 | ARYL HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D.E. Shaw Research, LLC (US) | 2022-08-17 | — | — | EP | disclosed |