Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919968 | 0.89 | TSHR (0.74) | SMN1; SMN2GAAPKMKMT2AMEN1 | |
| SCHEMBL34615 | 0.82 | MEN1 (0.73) | SMN1; SMN2GAAPKMKMT2AMEN1 | |
| SCHEMBL19667171 | 0.82 | HSD17B10 (0.77) | SMN1; SMN2GAAPKMKMT2AMEN1 | |
| SCHEMBL11184367 | 0.82 | CYP3A4 (0.75) | SMN1; SMN2GAAPKMTSHRLMNA | |
| SCHEMBL3920036 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2GAAPKMKMT2AMEN1 | |
| SCHEMBL17478854 | 0.79 | PKM (0.97) | SMN1; SMN2GAAPKMKMT2AMEN1 | |
| SCHEMBL8540322 | 0.79 | POLB (0.73) | SMN1; SMN2GAAPKMKMT2AMEN1 | |
| SCHEMBL4760475 | 0.78 | LMNA (0.74) | SMN1; SMN2KMT2AMEN1LMNAPOLB | |
| SCHEMBL16735251 | 0.78 | LMNA (0.62) | SMN1; SMN2GAAPKMKMT2AMEN1 | |
| SCHEMBL5736053 | 0.78 | POLB (0.58) | SMN1; SMN2GAAPKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109928931-B | Sulfonamide derivative containing benzimidazole structure and preparation method and application thereof | 沈阳药科大学 | 2022-09-02 | — | — | CN | disclosed |