Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1667311 | 0.84 | TSHR (0.40) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1238012 | 0.84 | MAPT (0.60) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL28161235 | 0.83 | TSHR (0.37) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| SCHEMBL28332007 | 0.82 | TSHR (0.41) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| SCHEMBL2946080 | 0.82 | TSHR (0.59) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL2904055 | 0.82 | TSHR (0.39) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| Bromide SCHEMBL28073958 | 0.80 | TSHR (0.57) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| SCHEMBL28946665 | 0.80 | TSHR (0.37) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| SCHEMBL28946675 | 0.78 | BBOX1 (0.41) | MAPTGALR3BLMSMN1; SMN2LMNA | |
| SCHEMBL10099799 | 0.77 | TSHR (0.47) | SMN1; SMN2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173104-A1 | MANUFACTURING METHOD OF RECORDING MEDIUM, INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORPORATION (JP) | 2010-07-08 | — | — | US | disclosed |
| EP-2004416-B1 | INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORP (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-2004416-A4 | MANUFACTURING METHOD OF RECORDING MEDIUM, INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORP (JP) | 2009-08-05 | — | — | EP | disclosed |
| EP-2004416-A1 | MANUFACTURING METHOD OF RECORDING MEDIUM, INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007116776-A1 | MANUFACTURING METHOD OF RECORDING MEDIUM, INKJET RECORDING MEDIUM, AND METHOD OF MANUFACTURING THE SAME | FUJIFILM CORPORATION (JP) | 2007-10-18 | — | — | WO | disclosed |