SCHEMBL29888451

SCHEMBL29888451

O=c1ccc2coc3ccccc3c-2c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.49
MAOB P27338 6/20 0.42
PTPN1 P18031 3/20 0.42
MAOA P21397 2/20 0.42
FTO Q9C0B1 1/20 0.40
PTPN2 P17706 1/20 0.39
PLA2G2A P14555 1/20 0.39
PLA2G4A P47712 1/20 0.39
NISCH Q9Y2I1 1/20 0.37
GSK3B P49841 2/20 0.37
CDK2 P24941 1/20 0.37
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CTRC Q99895 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11261922 1.00 MIF (0.49) MIFMAOBPTPN1MAOAFTO
SCHEMBL23356548 0.75 MAOB (0.40) MIFMAOBPTPN1MAOAFTO
SCHEMBL11663324 0.73 AR (0.43) MIFMAOBMAOAFTOKDM4E
SCHEMBL2490828 0.71 CHRM2 (0.50) MIFMAOBPTPN1MAOAFTO
SCHEMBL7507706 0.69 MIF (0.46) MIFMAOBPTPN1MAOAFTO
SCHEMBL1310425 0.69 PIN1 (0.56) MIFMAOBPTPN1MAOAFTO
SCHEMBL25567373 0.68 GSK3B (0.49) MIFMAOBPTPN1MAOAFTO
SCHEMBL23300745 0.68 PTPN1 (0.46) MIFMAOBPTPN1MAOAPTPN2
Isoflavone SCHEMBL8028 0.67 ALDH1A1 (0.66) MIFMAOBPTPN1MAOANISCH
SCHEMBL19180204 0.67 MIF (0.44) MIFMAOBPTPN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220305147-A1 SYNTHETIC CANNABINOID COMBINATION THERAPY COMPOSITIONS AND METHODS FOR PERSONALIZED AND TARGETED THERAPIES INCLUDING THE TREATMENT OF INFECTIOUS DISEASES VYRIPHARM ENTERPRISES, INC. 2022-09-29 US claimed
EP-4514340-A1 TREATMENT OF THE ADVERSE CARDIOVASCULAR EFFECTS OF CANNABINOIDS Greenstone Biosciences, Inc. (US) 2025-03-05 EP disclosed
WO-2023212130-A1 TREATMENT OF THE ADVERSE CARDIOVASCULAR EFFECTS OF CANNABINOIDS GreenStone Biosciences, Inc. (US) 2023-11-02 WO disclosed
US-20220305147-A1 SYNTHETIC CANNABINOID COMBINATION THERAPY COMPOSITIONS AND METHODS FOR PERSONALIZED AND TARGETED THERAPIES INCLUDING THE TREATMENT OF INFECTIOUS DISEASES VYRIPHARM ENTERPRISES, INC. 2022-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220305147-A1 SYNTHETIC CANNABINOID COMBINATION THERAPY COMPOSITIONS AND METHODS FOR PERSONALIZED AND TARGETED THERAPIES INCLUDING THE TREATMENT OF INFECTIOUS DISEASES CNR2, CNR1, FAAH MIF 4364/4885MAOB 2801/4885PTPN1 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.