SCHEMBL29888498

SCHEMBL29888498

CC(C)(C)OC(=O)NCc1ccc2nc(NCCCn3ccnc3)sc2c1

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 5/20 0.61
NAMPT P43490 7/20 0.56
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24648675 1.00 QPCT (0.61) QPCTNAMPTLMNASMN1; SMN2TP53
SCHEMBL29888531 0.81 QPCT (0.52) QPCTNAMPTLMNASMN1; SMN2KMT2A
SCHEMBL24648674 0.81 QPCT (0.52) QPCTNAMPTLMNASMN1; SMN2KMT2A
SCHEMBL29888527 0.79 NAMPT (0.47) QPCTNAMPTLMNASMN1; SMN2TP53
SCHEMBL29889141 0.78 NAMPT (0.46) QPCTNAMPTLMNASMN1; SMN2TP53
SCHEMBL77764 0.77 QPCT (1.00) QPCTSMN1; SMN2TP53MAPK1KMT2A
SCHEMBL5217150 0.75 QPCT (0.76) QPCTNAMPTALOX15
SCHEMBL78603 0.75 QPCT (1.00) QPCTLMNASMN1; SMN2MAPK1KMT2A
SCHEMBL27400268 0.74 DYRK1A (0.49) NAMPT
SCHEMBL4781044 0.74 L3MBTL1 (0.60) QPCTNAMPTLMNASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570647-B2 Amino benzothiazole compounds for treatment of antibiotic resistant bacteria SAINT LOUIS UNIVERSITY (US) 2026-03-10 US disclosed
US-20220267312-A1 AMINO BENZOTHIAZOLE COMPOUNDS FOR TREATMENT OF ANTIBIOTIC RESISTANT BACTERIA SAINT LOUIS UNIVERSITY (US) 2022-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220267312-A1 AMINO BENZOTHIAZOLE COMPOUNDS FOR TREATMENT OF ANTIBIOTIC RESISTANT BACTERIA BCAT2, BCAT1, ABAT QPCT 29/4885NAMPT 503/4885LMNA 3561/4885
US-12570647-B2 Amino benzothiazole compounds for treatment of antibiotic resistant bacteria BCAT1, BCAT2, IL4I1 QPCT 160/4885NAMPT 4131/4885LMNA 1975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.