Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884919 | 1.00 | SLC26A6 (0.53) | SLC26A6TSHRPTGESALOX5HTT | |
| SCHEMBL31526364 | 0.85 | TSHR (0.65) | SLC26A6TSHRLMNAALDH1A1PKM | |
| SCHEMBL892112 | 0.78 | SLC26A6 (0.49) | SLC26A6PTGESALOX5HTTLMNA | |
| SCHEMBL23461557 | 0.76 | HTT (0.50) | SLC26A6TSHRPTGESHTTLMNA | |
| SCHEMBL892484 | 0.76 | SLC26A6 (0.55) | SLC26A6PTGESALOX5HTTLMNA | |
| SCHEMBL23462015 | 0.74 | BRD4 (0.50) | SLC26A6TSHRHTTLMNAALDH1A1 | |
| SCHEMBL30091541 | 0.73 | PTGES (0.53) | SLC26A6PTGESALOX5LMNAALDH1A1 | |
| SCHEMBL15957045 | 0.73 | PTGES (0.53) | SLC26A6PTGESALOX5LMNAALDH1A1 | |
| SCHEMBL29799514 | 0.72 | TRPM8 (0.46) | SLC26A6PTGESALOX5HTTLMNA | |
| SCHEMBL5779014 | 0.72 | PDE3B (0.49) | SLC26A6TSHRPTGESALOX5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003296-A | Compounds and methods for treating cystic fibrosis | 弗拉特利发现实验室有限责任公司 | 2022-09-02 | — | — | CN | disclosed |