Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 12/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 4/20 | 0.44 |
| ▸ | BRAF | P15056 | 4/20 | 0.44 |
| ▸ | TEK | Q02763 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2261930 | 1.00 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C19CLK4HSD17B10 | |
| SCHEMBL1265630 | 0.81 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C19CLK4HSD17B10 | |
| SCHEMBL29890921 | 0.79 | MAPT (0.43) | CYP1A2CYP2D6CYP2C19CLK4HSD17B10 | |
| SCHEMBL14970106 | 0.79 | MAPT (0.43) | CYP1A2CYP2D6CYP2C19CLK4HSD17B10 | |
| SCHEMBL558697 | 0.76 | ASIC3 (0.49) | CYP1A2CYP2D6CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL1445127 | 0.76 | MIF (0.49) | CYP1A2CYP2D6CYP2C19CLK4HSD17B10 | |
| SCHEMBL29890894 | 0.75 | MAPT (0.41) | CYP1A2CYP2D6CYP2C19CLK4HSD17B10 | |
| SCHEMBL28507574 | 0.75 | MAPT (0.41) | CYP1A2CYP2D6CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL10272461 | 0.75 | CHRNA7 (0.43) | CYP1A2CYP2D6CYP2C19CLK4HSD17B10 | |
| SCHEMBL10220817 | 0.75 | MAPT (0.41) | CYP1A2CYP2D6CYP2C19CLK4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262803-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | Chungdu Anticancer Bioscience Ltd (CN) | 2024-08-08 | — | — | US | disclosed |
| WO-2022199654-A1 | HETEROARYL-HETEROARYL-O-PHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER DISORDERS | Chengdu Anticancer Bioscience, Ltd. (CN) | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262803-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CYP27A1, PNLIP, GOT2 | CYP1A2 655/4885CYP2D6 705/4885CYP2C19 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.