Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3876408 | 0.81 | DHODH (0.50) | ALDH1A1MAPTCYP11B1CYP11B2HTT | |
| SCHEMBL31051044 | 0.81 | DHODH (0.50) | ALDH1A1MAPTCYP11B1CYP11B2HTT | |
| SCHEMBL10205407 | 0.80 | CYP2A6 (0.56) | CYP2A6CYP3A4ALDH1A1CYP1A2MAPT | |
| SCHEMBL29889660 | 0.79 | MAPT (0.49) | MAPTCYP11B1CYP11B2LMNA | |
| SCHEMBL2489325 | 0.79 | MAPT (0.49) | MAPTCYP11B1CYP11B2LMNA | |
| SCHEMBL20541087 | 0.78 | CYP2A6 (0.70) | CYP2A6CYP3A4ALDH1A1CYP1A2MAPT | |
| SCHEMBL30026143 | 0.78 | CYP2A6 (0.70) | CYP2A6CYP3A4ALDH1A1CYP1A2MAPT | |
| SCHEMBL31635952 | 0.78 | PTGS2 (0.64) | CYP2A6CYP3A4ALDH1A1CYP1A2MAPT | |
| SCHEMBL2592406 | 0.78 | CYP2A6 (0.57) | CYP2A6CYP3A4ALDH1A1CYP1A2MAPT | |
| SCHEMBL30032 | 0.78 | PTGS2 (0.64) | CYP2A6CYP3A4ALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262803-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | Chungdu Anticancer Bioscience Ltd (CN) | 2024-08-08 | — | — | US | disclosed |
| WO-2022199654-A1 | HETEROARYL-HETEROARYL-O-PHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER DISORDERS | Chengdu Anticancer Bioscience, Ltd. (CN) | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262803-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CYP27A1, PNLIP, GOT2 | CYP2A6 564/4885CYP3A4 1394/4885ALDH1A1 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.