Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989002 | 1.00 | TAAR1 (0.39) | TAAR1L3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL5314701 | 0.78 | L3MBTL1 (0.43) | TAAR1L3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL13246595 | 0.78 | L3MBTL1 (0.43) | TAAR1L3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL13246614 | 0.78 | L3MBTL1 (0.43) | TAAR1L3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL2999926 | 0.77 | L3MBTL1 (0.37) | TAAR1L3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL5315676 | 0.77 | L3MBTL1 (0.37) | TAAR1L3MBTL1CHRM2CHRNB2CHRNA7 | |
| SCHEMBL13246612 | 0.77 | L3MBTL1 (0.37) | TAAR1L3MBTL1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL2985980 | 0.76 | L3MBTL1 (0.39) | TAAR1L3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL2993721 | 0.75 | SLC6A3 (0.38) | TAAR1CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL9934708 | 0.73 | GABRA1 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184991-A1 | PREPARATION OF TERAZOLE DERIVATIVES | SEDELMEIER GOTTFRIED | 2010-07-22 | — | — | US | disclosed |
| US-20080200687-A1 | Preparation of Terazole Derivatives | SEDELMEIER GOTTFRIED | 2008-08-21 | — | — | US | disclosed |
| EP-1907378-A1 | PREPARATION OF TERAZOLE DERIVATIVES | Novartis AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009716-A1 | PREPARATION OF TERAZOLE DERIVATIVES | NOVARTIS AG (CH) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200687-A1 | Preparation of Terazole Derivatives | TERB1, TALDO1, TERT | TAAR1 985/4885L3MBTL1 2483/4885CHRM2 1270/4885 |
| US-20100184991-A1 | PREPARATION OF TERAZOLE DERIVATIVES | TERB1, TALDO1, TERT | TAAR1 985/4885L3MBTL1 2483/4885CHRM2 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.