Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.70 |
| ▸ | MAOB | P27338 | 3/20 | 0.67 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.58 |
| ▸ | HPD | P32754 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26933189 | 1.00 | NR4A2 (0.70) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL4403920 | 0.93 | MRGPRX4 (0.63) | NR4A2MAOBMRGPRX4 | |
| SCHEMBL12746033 | 0.92 | MRGPRX4 (0.64) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL7764407 | 0.83 | NR4A2 (0.68) | NR4A2MAOBSRD5A2PTPN1NR4A1 | |
| SCHEMBL7908051 | 0.83 | SRD5A2 (0.85) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL339009 | 0.83 | NR4A2 (1.00) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL30207018 | 0.83 | NR4A2 (1.00) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL3442746 | 0.81 | NR4A2 (0.79) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| Hydrochloric Acid SCHEMBL4748074 | 0.81 | NR4A2 (0.97) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL5268537 | 0.80 | NR4A2 (0.59) | NR4A2MAOBSMPD1SRD5A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313951-A1 | 1,3-SUBSTITUTED CYCLOBUTYL DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022201097-A1 | 1,3-SUBSTITUTED CYCLOBUTYL DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2022-09-29 | — | — | WO | disclosed |