Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | FOS | P01100 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367454 | 0.84 | CA2 (0.59) | MAPK1LMNAALDH1A1 | |
| SCHEMBL17436817 | 0.84 | SHBG (0.66) | SHBGMAPK1TAAR1TSHRCYP3A4 | |
| SCHEMBL15147254 | 0.81 | SHBG (0.55) | SHBGMAPK1TAAR1TSHRCYP3A4 | |
| SCHEMBL19923816 | 0.80 | SHBG (0.66) | SHBGMAPK1TAAR1TSHRCYP3A4 | |
| SCHEMBL29961299 | 0.80 | SHBG (0.70) | SHBGMAPK1TAAR1TSHRCYP3A4 | |
| SCHEMBL1261582 | 0.80 | SHBG (0.70) | SHBGMAPK1TAAR1TSHRCYP3A4 | |
| SCHEMBL8106424 | 0.80 | SHBG (0.65) | SHBGMAPK1TAAR1TSHRCYP3A4 | |
| SCHEMBL14008440 | 0.79 | SHBG (0.53) | SHBGMAPK1TAAR1TSHRCYP3A4 | |
| SCHEMBL31063566 | 0.79 | SLC6A4 (0.58) | SHBG | |
| SCHEMBL30217506 | 0.79 | SHBG (1.00) | SHBGMAPK1TAAR1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401388-B1 | FRAGRANCE AND FLAVOUR COMPOSITIONS | GIVAUDAN SA (CH) | 2010-06-16 | — | — | EP | claimed |
| US-20050042255-A1 | Fragrance and flavour compositions | GIVAUDAN SA (CH) | 2005-02-24 | — | — | US | claimed |
| EP-1401388-A2 | FRAGRANCE AND FLAVOUR COMPOSITIONS | Givaudan SA (CH) | 2004-03-31 | — | — | EP | claimed |
| WO-2003002084-A2 | FRAGRANCE AND FLAVOUR COMPOSITIONS | GIVAUDAN SA (CH) | 2003-01-09 | — | — | WO | claimed |
| EP-1269982-A1 | Fragrance and flavour compositions | Givaudan SA (CH) | 2003-01-02 | — | — | EP | claimed |
| US-7777084-B2 | Cyclopropanation process | GIVAUDAN SA (CH) | 2010-08-17 | — | — | US | disclosed |
| US-7777084-B2 | Cyclopropanation process | GIVAUDAN SA (CH) | 2010-08-17 | — | — | US | disclosed |
| US-7777084-B2 | Cyclopropanation process | GIVAUDAN SA (CH) | 2010-08-17 | — | — | US | disclosed |
| EP-1401388-B1 | FRAGRANCE AND FLAVOUR COMPOSITIONS | GIVAUDAN SA (CH) | 2010-06-16 | — | — | EP | disclosed |
| US-7704942-B2 | Fragrance and flavour compositions | GIVAUDAN SA (CH) | 2010-04-27 | — | — | US | disclosed |
| EP-1828087-B1 | CYCLOPROPANATION PROCESS | GIVAUDAN SA (CH) | 2008-12-03 | — | — | EP | disclosed |
| EP-1828087-B1 | CYCLOPROPANATION PROCESS | GIVAUDAN SA (CH) | 2008-12-03 | — | — | EP | disclosed |
| US-20080275256-A1 | Cyclopropanation Process | GIVAUDAN SA (CH) | 2008-11-06 | — | — | US | disclosed |
| US-20080275256-A1 | Cyclopropanation Process | GIVAUDAN SA (CH) | 2008-11-06 | — | — | US | disclosed |
| EP-1828087-A1 | CYCLOPROPANATION PROCESS | Givaudan SA (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066436-A1 | CYCLOPROPANATION PROCESS | GIVAUDAN SA (CH) | 2006-06-29 | — | — | WO | disclosed |
| US-20050042255-A1 | Fragrance and flavour compositions | GIVAUDAN SA (CH) | 2005-02-24 | — | — | US | disclosed |
| EP-1401388-A2 | FRAGRANCE AND FLAVOUR COMPOSITIONS | Givaudan SA (CH) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003002084-A2 | FRAGRANCE AND FLAVOUR COMPOSITIONS | GIVAUDAN SA (CH) | 2003-01-09 | — | — | WO | disclosed |
| EP-1269982-A1 | Fragrance and flavour compositions | Givaudan SA (CH) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050042255-A1 | Fragrance and flavour compositions | C5, FAAH2, TRPA1 | SHBG 2300/4885MAPK1 3634/4885TAAR1 43/4885 |
| US-20080275256-A1 | Cyclopropanation Process | C9, TRPA1, HACL2 | SHBG 4585/4885MAPK1 3873/4885TAAR1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.