Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KHK | P50053 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | USP1 | O94782 | 4/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23411312 | 1.00 | HTR2C (0.50) | HTR2CADRB1GABRA1GABRB2MEN1 | |
| SCHEMBL23411539 | 0.84 | HTR6 (0.47) | HTR2CADRB1GABRA1HTR6USP1 | |
| SCHEMBL29892599 | 0.84 | HTR6 (0.47) | HTR2CADRB1GABRA1HTR6USP1 | |
| Hydrochloric Acid SCHEMBL31582970 | 0.79 | HTR2C (0.50) | HTR2CADRB1GABRA1GABRB2 | |
| SCHEMBL25172210 | 0.79 | MGLL (0.52) | MEN1KMT2AKCNJ6KCNJ3MGLL | |
| SCHEMBL23412142 | 0.75 | HTR2C (0.47) | HTR2CADRB1GABRA1GABRB2MEN1 | |
| SCHEMBL23410958 | 0.74 | HTR3A (0.42) | ADRB1KMT2AUSP1MGLL | |
| SCHEMBL18418196 | 0.74 | MKNK1 (0.43) | KMT2AUSP1MGLL | |
| SCHEMBL29891976 | 0.74 | GPR119 (0.62) | MEN1KMT2AMGLL | |
| SCHEMBL23411375 | 0.74 | GPR119 (0.62) | MEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| EP-4065574-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2022-10-05 | — | — | EP | disclosed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |