SCHEMBL2989193

SCHEMBL2989193

CO[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.41
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
LTA4H P09960 3/20 0.35
TSHR P16473 4/20 0.33
MAPK1 P28482 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL991780 0.77 CA4 (0.41) CA4CA12CA1CA2CA7
SCHEMBL1658642 0.77 CA4 (0.41) CA4CA12CA1CA2CA7
SCHEMBL704391 0.72 CA4 (0.38) CA4CA12CA1CA2CA7
SCHEMBL675369 0.71 LTA4H (0.32) LTA4HTSHRALDH1A1
SCHEMBL272624 0.70 MAPK1 (0.37) CA4TSHRMAPK1ALDH1A1
SCHEMBL3529369 0.70 MIF (0.35) CA4TSHRALDH1A1LMNASMN1; SMN2
SCHEMBL15161748 0.70 ESR1 (0.33) CA4TSHRKMT2AMEN1MAPT
SCHEMBL5165921 0.70 LTA4H (0.37) CA4LTA4HTSHRMAPK1KMT2A
SCHEMBL27161 0.69 MAPK1 (0.36) CA4CA12CA1CA2CA7
SCHEMBL16005679 0.69 LTA4H (0.43) CA4CA1CA2CA9LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070282121-A1 INTERMEDIATES FOR THE SYNTHESIS OF POLYPROPIONATE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-12-06 US claimed
US-7297807-B1 Intermediates for the synthesis of polypropionate antibiotics THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2007-11-20 US claimed
EP-3128399-B1 TRANSPARENT LAMINATED FILM FOR PEN INPUT DEVICE AND MANUFACTURING METHOD THEREOF DAICEL CORP (JP) 2023-07-19 EP disclosed
CN-115029080-A Adhesive sheet 日东电工(上海松江)有限公司 2022-09-09 CN disclosed
CN-111093963-B Formed body 株式会社大赛璐 2022-02-25 CN disclosed
CN-107735253-B Damage recovery membrane 株式会社大赛璐 2021-06-01 CN disclosed
US-20200284950-A1 PLASTIC LENS DAICEL CORPORATION (JP) 2020-09-10 US disclosed
US-20200271829-A1 PLASTIC LENS DAICEL CORPORATION (JP) 2020-08-27 US disclosed
EP-3683602-A1 PLASTIC LENS Daicel Corporation (JP) 2020-07-22 EP disclosed
EP-3683603-A1 PLASTIC LENS Daicel Corporation (JP) 2020-07-22 EP disclosed
US-10719176-B2 Transparent laminated film for pen input device and manufacturing method thereof DAICEL CORPORATION (JP) 2020-07-21 US disclosed
US-20040054102-A1 Olefin polymerization catalyst, catalyst component for olefin polymerization, method of storing these, and process for producing olefin polymer SUNALLOMER LTD. (JP) 2004-03-18 US disclosed
EP-1359166-A1 OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD OF STORING THESE, AND PROCESS FOR PRODUCING OLEFIN POLYMER Sunallomer Ltd (JP) 2003-11-05 EP disclosed
WO-2003035708-A1 SOLID COCATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST SYSTEM THEREOF SUNALLOMER LTD (JP) 2003-05-01 WO disclosed
EP-0653472-B1 Curable organopolysiloxane composition containing adhesion promoter DOW CORNING TORAY SILICONE (JP) 2000-01-19 EP disclosed
US-5527932-A REACTION PRODUCT OF AMINE, UNSATURATED EPOXY COMPOUNDS AND SILICON COMPOUND WITH AT LEAST TWO SILICON-BONDED ALKOXY GROUPS DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-06-18 US disclosed
US-5445891-A A reaction product of an amine compound with an aliphatically unsaturated epoxy compound DOW CORNING TORAY SILICONCO., LTD. (JP) 1995-08-29 US disclosed
EP-0653472-A2 Curable organopolysiloxane composition containing adhesion promoter Dow Corning Toray Silicone Company, Limited (JP) 1995-05-17 EP disclosed
EP-0375994-B1 Process for preparing polycarbosilanes; polycarbosilanes obtained by this process KALI CHEMIE AG (DE) 1994-03-16 EP disclosed
US-5087685-A PROCESS FOR PREPARING POLYCARBOSILANES AND NEW POLYCARBOSILANES KALI-CHEMIE AKTIENGESELLSCHAFT (DE) 1992-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070282121-A1 INTERMEDIATES FOR THE SYNTHESIS OF POLYPROPIONATE ANTIBIOTICS DHPS, EMG1, RPN1 CA4 4411/4885CA12 4749/4885CA1 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.