SCHEMBL991780

SCHEMBL991780

CO[Si](C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.41
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
LTA4H P09960 3/20 0.35
TSHR P16473 4/20 0.33
MAPK1 P28482 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676902 0.78 TSHR (0.32) CA4TSHRLMNAALOX12ACHE
SCHEMBL1658642 0.77 CA4 (0.41) CA4CA12CA1CA2CA7
SCHEMBL2989193 0.77 CA4 (0.41) CA4CA12CA1CA2CA7
SCHEMBL5486213 0.76 CA4 (0.31) CA4
SCHEMBL9327347 0.74 LTA4H (0.35) LTA4HTSHRMAPK1KMT2AALDH1A1
SCHEMBL704391 0.72 CA4 (0.38) CA4CA12CA1CA2CA7
SCHEMBL55165 0.71
SCHEMBL8719 0.71 TSHR (0.39) CA4CA12CA1CA2CA7
SCHEMBL7631451 0.71 TSHR (0.39) CA4CA12CA1CA2CA7
SCHEMBL22607984 0.69 TSHR (0.37) CA4CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110527246-A The modified granulated material of the polyether-ether-ketone of low thermal conductivity and its application ZHEJIANG PFLUON TECH CO LTD 2019-12-03 CN claimed
CN-118206421-A Dihydro fulvene derivative and preparation method thereof 河南省科学院化学研究所有限公司 2024-06-18 CN disclosed
CN-118184712-A Method for interfering with continuous movement of carbon atoms in organic molecules 河南省科学院化学研究所有限公司 2024-06-14 CN disclosed
US-11882762-B2 Formulation and method for preparation of organic electronic devices FLEXENABLE TECHNOLOGY LIMITED (GB) 2024-01-23 US disclosed
EP-3128399-B1 TRANSPARENT LAMINATED FILM FOR PEN INPUT DEVICE AND MANUFACTURING METHOD THEREOF DAICEL CORP (JP) 2023-07-19 EP disclosed
EP-3323159-B1 COMPOSITION COMPRISING ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2023-01-04 EP disclosed
CN-115029080-A Adhesive sheet 日东电工(上海松江)有限公司 2022-09-09 CN disclosed
CN-111093963-B Formed body 株式会社大赛璐 2022-02-25 CN disclosed
CN-113314674-A Printable p-type doping pastes for solar cells or semiconductors and doping methods 东丽先端材料研究开发(中国)有限公司 2021-08-27 CN disclosed
CN-107735253-B Damage recovery membrane 株式会社大赛璐 2021-06-01 CN disclosed
US-20020177660-A1 Polymer material and polymer film HITACHI CABLE, LTD. AND NIPPON PAINT CO., LTD. 2002-11-28 US disclosed
US-20020150368-A1 Polymer waveguides and process for producing the same HITACHI CABLE, LTD. 2002-10-17 US disclosed
EP-0725315-B1 Photosensitive resin composition and method for forming pattern using the same NIPPON PAINT CO LTD (JP) 2001-05-02 EP disclosed
EP-0653472-B1 Curable organopolysiloxane composition containing adhesion promoter DOW CORNING TORAY SILICONE (JP) 2000-01-19 EP disclosed
EP-0725315-A2 Photosensitive resin composition and method for forming pattern using the same Nippon Paint Co., Ltd. (JP) 1996-08-07 EP disclosed
US-5527932-A REACTION PRODUCT OF AMINE, UNSATURATED EPOXY COMPOUNDS AND SILICON COMPOUND WITH AT LEAST TWO SILICON-BONDED ALKOXY GROUPS DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-06-18 US disclosed
US-5445891-A A reaction product of an amine compound with an aliphatically unsaturated epoxy compound DOW CORNING TORAY SILICONCO., LTD. (JP) 1995-08-29 US disclosed
EP-0653472-A2 Curable organopolysiloxane composition containing adhesion promoter Dow Corning Toray Silicone Company, Limited (JP) 1995-05-17 EP disclosed
EP-0375994-B1 Process for preparing polycarbosilanes; polycarbosilanes obtained by this process KALI CHEMIE AG (DE) 1994-03-16 EP disclosed
EP-0375994-A1 Process for preparing polycarbosilanes; polycarbosilanes obtained by this process Kali-Chemie Aktiengesellschaft (DE) 1990-07-04 EP disclosed