Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPRA | P18433 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9466731 | 0.79 | CA1 (0.48) | CA1CA2 | |
| SCHEMBL16966402 | 0.79 | ALDH1A1 (0.33) | CA1CA2KEAP1 | |
| SCHEMBL97872 | 0.79 | KEAP1 (0.48) | TSHRSMN1; SMN2CA1CA2KEAP1 | |
| SCHEMBL5387287 | 0.76 | KEAP1 (0.32) | CA2KEAP1 | |
| SCHEMBL2539925 | 0.76 | NR3C1 (0.36) | KEAP1 | |
| SCHEMBL2206469 | 0.76 | PSIP1 (0.46) | SMN1; SMN2 | |
| SCHEMBL1607675 | 0.76 | KEAP1 (0.53) | SMN1; SMN2CA1CA2KEAP1MMP1 | |
| SCHEMBL1761790 | 0.75 | KEAP1 (0.31) | KEAP1 | |
| SCHEMBL5400771 | 0.75 | TSHR (0.46) | TSHRSMN1; SMN2 | |
| SCHEMBL5487764 | 0.75 | PSIP1 (0.33) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012611-B1 | ELECTROPHOTOGRAPHIC ELEMENT | Ricoh Company, Ltd (JP) | 1983-10-05 | — | — | EP | claimed |
| EP-0012611-A2 | Electrophotographic element | Ricoh Company, Ltd (JP) | 1980-06-25 | — | — | EP | claimed |
| CN-117264175-A | Polyisocyanate composition, aqueous coating composition, coated substrate, and method for producing polyisocyanate composition | 旭化成株式会社 | 2023-12-22 | — | — | CN | disclosed |
| CN-117229476-A | Polyisocyanate composition, blocked polyisocyanate composition, polyurethane resin composition, coating composition, and coated substrate | 旭化成株式会社 | 2023-12-15 | — | — | CN | disclosed |
| US-20230265087-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | EyePoint, Inc. | 2023-08-24 | — | — | US | disclosed |
| US-11613534-B2 | Small molecule activators of Tie-2 | EyePoint Pharmaceuticals, Inc. (US) | 2023-03-28 | — | — | US | disclosed |
| US-20210147404-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | EyePoint, Inc. | 2021-05-20 | — | — | US | disclosed |
| WO-2021086904-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | Aerpio Pharmaceuticals, Inc. (US) | 2021-05-06 | — | — | WO | disclosed |
| US-10889907-B2 | Cyanide-free acidic matte silver electroplating compositions and methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2021-01-12 | — | — | US | disclosed |
| CN-106822174-B | Carbonic anhydrase inhibitor and preparation method thereof based on temperature sensitive cyclodextrin | 上海大学 | 2019-10-11 | — | — | CN | disclosed |
| EP-2071057-B1 | ELECTROPLATING COPPER-TIN ALLOY | ROHM & HAAS ELECT MAT (US) | 2019-01-23 | — | — | EP | disclosed |
| US-6521614-B1 | Anticoagulant agents for treatment and prevention of thromboembolic disorders | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-02-18 | — | — | US | disclosed |
| EP-0960104-A1 | N-(AMIDINOPHENYL)-N'-(SUBST.)-3H-2,4-BENZODIAZEPIN-3-ONE DERIVATIVES AS FACTOR XA INHIBITORS | Du Pont Pharmaceuticals Company (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1997038984-A1 | N-(AMIDINOPHENYL)-N'-(SUBST.)-3H-2,4-BENZODIAZEPIN-3-ONE DERIVATIVES AS FACTOR XA INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-10-23 | — | — | WO | disclosed |
| EP-0376650-B1 | Liquid developer for electrostatic photography | FUJI PHOTO FILM CO LTD (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5073471-A | Comprising dispersed resin grains of an acrylic polymer of an unsaturated ester, an acrylic stabilizer and an oligomer; antisoilants; antisticking agents | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| US-5073470-A | Resin grains of monofunctial monomer polymerized with macromonomer having one terminal double bond, dispersion stabilizing resin | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| US-5006441-A | Redespersibility; storage stability; antisoilants; durability and fixability; image-reproduction | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0376650-A2 | Liquid developer for electrostatic photography | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |
| US-3947450-A | Benzoxanthene and benzothioxanthene dicarboxylic acid imide dyestuffs and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147404-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | TIE1, TEK, KDR | ACP1 680/4885PTPN1 3369/4885PTPN2 2231/4885 |
| US-11613534-B2 | Small molecule activators of Tie-2 | TIE1, TEK, KDR | ACP1 680/4885PTPN1 3369/4885PTPN2 2231/4885 |
| US-20230265087-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | TIE1, TEK, KDR | ACP1 680/4885PTPN1 3369/4885PTPN2 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.