Trolamine

Trolamine

SCHEMBL2989362

C=CCOP(=O)(O)O.CCOCC.OCCN(CCO)CCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LPAR3 Q9UBY5 2/20 0.33
PPARD Q03181 2/20 0.33
LPAR2 Q9HBW0 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL11778978 0.90 LPAR2 (0.39) TDP1LPAR3LPAR2FNTAFNTB
Ether SCHEMBL17529974 0.89 PPARD (0.38) LPAR3PPARDLPAR2FNTAFNTB
Ether SCHEMBL2867631 0.87 LPAR3 (0.41) MEN1POLBKMT2ALPAR3PPARD
2-Ethoxyethanol SCHEMBL8226551 0.82 ALDH1A1 (0.48) MEN1POLBKMT2ALPAR3PPARD
Dihydroxyacetone SCHEMBL2519348 0.81 LPAR3 (0.35) LPAR3PPARDLPAR2FNTAFNTB
Trolamine SCHEMBL28769353 0.78 MEN1 (0.38) MEN1POLBKMT2A
Alcohol SCHEMBL28740948 0.77 LPAR3 (0.42) LPAR3PPARDLPAR2FNTAFNTB
Alcohol SCHEMBL27633532 0.77 LPAR3 (0.42) LPAR3PPARDLPAR2FNTAFNTB
Alcohol SCHEMBL11778974 0.77 LPAR3 (0.42) LPAR3PPARDLPAR2FNTAFNTB
Trolamine SCHEMBL9232394 0.77 PPARD (0.48) MEN1KMT2ATDP1LPAR3PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8425889-B2 Cleansing composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-04-23 US disclosed
EP-1669055-B1 DETERGENT COMPOSITION ASAHI KASEI CHEMICALS CORP (JP) 2010-08-25 EP disclosed
US-20070122371-A1 Cleansing composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2007-05-31 US disclosed
EP-1669055-A1 DETERGENT COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2006-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070122371-A1 Cleansing composition CUTA, DSG1, NAAA MEN1 4079/4885POLB 1045/4885KMT2A 957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.