Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | GLA | P06280 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736477 | 1.00 | KDM4E (0.59) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL2795205 | 0.81 | KDM4E (0.67) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL6007662 | 0.78 | CHUK (0.53) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL6008260 | 0.78 | KIF11 (0.58) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL28300282 | 0.77 | ALK (0.41) | ALDH1A1HPGDNOS3NOS1NOS2 | |
| SCHEMBL12377872 | 0.76 | SLC6A4 (0.48) | ALDH1A1 | |
| SCHEMBL14022011 | 0.76 | AHR (0.47) | KDM4EALDH1A1HPGDNOS3NOS1 | |
| SCHEMBL10481569 | 0.76 | KDM4E (0.49) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL5993711 | 0.76 | KDM4E (0.59) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL12667296 | 0.76 | KMT2A (0.44) | ALDH1A1HPGDSMN1; SMN2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |