Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161638 | 0.88 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL29955688 | 0.82 | MITF (0.51) | ALDH1A1MAPTMEN1KMT2AALOX15 | |
| SCHEMBL6616975 | 0.78 | BCHE (0.43) | ALKITKALDH1A1MAPTMEN1 | |
| SCHEMBL14022011 | 0.78 | AHR (0.47) | NOS3NOS1NOS2ITKL3MBTL1 | |
| SCHEMBL21822535 | 0.78 | PIN1 (0.46) | ALKNOS3NOS1NOS2L3MBTL1 | |
| SCHEMBL4736477 | 0.77 | KDM4E (0.59) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL29894052 | 0.77 | KDM4E (0.59) | NOS3NOS1NOS2ALDH1A1HPGD | |
| SCHEMBL1306979 | 0.76 | ALOX15 (0.50) | ALKALDH1A1MAPTMEN1HPGD | |
| SCHEMBL30180875 | 0.76 | ALOX15 (0.69) | ALKALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL21822329 | 0.76 | ALOX15 (0.69) | ALKALDH1A1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912576-A | Cyclic annular or loop coil Diamines pyrimidine-hydroxamic acid and application thereof | 华东理工大学 | 2019-06-21 | — | — | CN | disclosed |