Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022011 | 0.77 | AHR (0.47) | KDM4ENOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL10481523 | 0.76 | KDM4E (0.52) | KDM4EGAAALDH1A1GLAHPGD | |
| SCHEMBL10481549 | 0.76 | TP53 (0.56) | KDM4EGAAALDH1A1 | |
| SCHEMBL29894052 | 0.76 | KDM4E (0.59) | KDM4EGAANOS3NOS1NOS2 | |
| SCHEMBL4736477 | 0.76 | KDM4E (0.59) | KDM4EGAANOS3NOS1NOS2 | |
| SCHEMBL28448478 | 0.74 | CHUK (0.50) | KDM4EGAAFASNNOS3NOS1 | |
| SCHEMBL21563919 | 0.74 | NOS3 (0.46) | NOS3NOS1NOS2ALKPIN1 | |
| SCHEMBL10481567 | 0.74 | KDM4E (0.50) | KDM4EGAAALDH1A1GLAHPGD | |
| SCHEMBL10481535 | 0.74 | KDM4E (0.58) | KDM4EGAAALDH1A1HPGD | |
| SCHEMBL28300282 | 0.74 | ALK (0.41) | NOS3NOS1NOS2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |