SCHEMBL29894147

SCHEMBL29894147

COc1ccc(C(OC[C@@H](CNC(=O)NCCCCCCO[Si](C)(C)C(C)(C)C)OC(=O)C(Cl)Cl)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.35
PLA2G10 O15496 1/20 0.35
PLA2G1B P04054 1/20 0.35
PLA2G5 P39877 1/20 0.35
KIF11 P52732 3/20 0.34
KMT2A Q03164 2/20 0.34
HDAC6 Q9UBN7 3/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CASR P41180 2/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
GSR P00390 1/20 0.32
SLC6A1 P30531 2/20 0.32
SLC6A11 P48066 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29142567 0.88 KIF11 (0.39) KIF11KMT2AHDAC6NPC1RAB9A
SCHEMBL27081233 0.87 MAPT (0.42) KIF11KMT2AHDAC6NPC1RAB9A
SCHEMBL27081229 0.87 MAPT (0.42) KIF11KMT2AHDAC6NPC1RAB9A
SCHEMBL29894243 0.82 PLA2G2A (0.34) PLA2G2APLA2G10PLA2G1BPLA2G5KIF11
SCHEMBL27081368 0.82 KIF11 (0.37) PLA2G2APLA2G10PLA2G1BPLA2G5KIF11
SCHEMBL27081364 0.82 KIF11 (0.37) PLA2G2APLA2G10PLA2G1BPLA2G5KIF11
SCHEMBL27082993 0.80 NPC1 (0.38) PLA2G2APLA2G10PLA2G1BPLA2G5KIF11
SCHEMBL27082995 0.80 NPC1 (0.38) PLA2G2APLA2G10PLA2G1BPLA2G5KIF11
SCHEMBL29142566 0.79 TBXAS1 (0.40) CASR
SCHEMBL27250536 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313984-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS Genscript USA Inc. (US) 2024-02-07 EP disclosed
CN-117222647-A Universal linker reagents for DNA synthesis 金斯瑞美国公司 2023-12-12 CN disclosed
WO-2022204102-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS GENSCRIPT USA INC. (US) 2022-09-29 WO disclosed