Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.43 |
| ▸ | KDM6B | O15054 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877385 | 0.85 | SIRT3 (0.65) | KDM4EP2RX7TDP1CYP1A2CYP3A4 | |
| SCHEMBL30674829 | 0.83 | KDM4C (0.49) | KDM4ETDP1CYP1A2CYP3A4SIRT3 | |
| SCHEMBL13518160 | 0.82 | KDM4E (0.55) | KDM4EP2RX7TDP1CYP1A2CYP3A4 | |
| SCHEMBL29467545 | 0.82 | ALDH1A1 (0.51) | KDM4ETDP1SIRT3ALDH1A1GLA | |
| SCHEMBL24997725 | 0.79 | KDM5A (0.45) | KDM4ETDP1SIRT3ALDH1A1GLA | |
| SCHEMBL1423953 | 0.79 | SIRT3 (0.43) | KDM4ETDP1SIRT3ALDH1A1GLA | |
| SCHEMBL30064136 | 0.79 | SIRT3 (0.43) | KDM4ETDP1SIRT3ALDH1A1GLA | |
| SCHEMBL286483 | 0.79 | TDP1 (0.71) | KDM4ETDP1SIRT3ADORA3ALDH1A1 | |
| SCHEMBL36668757 | 0.79 | TDP1 (0.71) | KDM4ETDP1SIRT3ADORA3ALDH1A1 | |
| SCHEMBL1967163 | 0.79 | TDP1 (0.50) | KDM4ETDP1CYP1A2CYP3A4SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
| CN-107056755-B | Five-ring heterocycles amides WNT pathway inhibitor | 苏州信诺维医药科技有限公司 | 2019-02-22 | — | — | CN | disclosed |
| WO-2018037223-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2018-03-01 | — | — | WO | disclosed |
| CN-107056755-A | Five-ring heterocycles amide-type WNT pathway inhibitors | 杭州雷索药业有限公司 | 2017-08-18 | — | — | CN | disclosed |
| US-20100184811-A1 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | BRIDGE BIORESEARCH RIGHTS (JERSEY) LIMITED (GB) | 2010-07-22 | — | — | US | disclosed |
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184811-A1 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | ODC1, OTC, ACACB | KDM4E 3169/4885P2RX7 3147/4885TDP1 3641/4885 |
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | KDM4E 3731/4885P2RX7 3064/4885TDP1 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.