SCHEMBL29896380

SCHEMBL29896380

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nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ENPEP Q07075 9/20 0.46
▸ PTPN1 P18031 1/20 0.43
▸ FURIN P09958 2/20 0.42
▸ F2 P00734 1/20 0.42
▸ PRSS1 P07477 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30532204 0.89 ENPEP (0.44) ENPEP
SCHEMBL31354608 0.87 ENPEP (0.48) ENPEPFURINF2
SCHEMBL5356649 0.86 ENPEP (0.53) ENPEP
SCHEMBL5356653 0.86 ENPEP (0.53) ENPEP
SCHEMBL30876813 0.83 BACE1 (0.45) ENPEPFURINPRSS1
SCHEMBL30601852 0.82 FOLH1 (0.43) FURINPRSS1
SCHEMBL30903264 0.82 GNAI3 (0.44) ENPEP
SCHEMBL31497760 0.82 GRIN2D (0.45) ENPEPFURIN
SCHEMBL28081105 0.81 BACE1 (0.47) FURIN
SCHEMBL31670467 0.81 ENPEP (0.52) ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11465965-B2 Double-headed protease inhibitor UBE INDUSTRIES, LTD. (JP) 2022-10-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11465965-B2 Double-headed protease inhibitor TMPRSS15, SPINT2, PRSS2 ENPEP 54/4885PTPN1 3161/4885FURIN 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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