Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538134 | 0.74 | DAO (0.53) | DAOMAPTAKR1C3AKR1C2 | |
| SCHEMBL28223316 | 0.72 | MAOA (0.52) | ALPLALPIPKMCA1CA2 | |
| SCHEMBL30716975 | 0.71 | DAO (0.53) | DAOAKR1C3AKR1C2 | |
| SCHEMBL14644667 | 0.71 | DAO (0.53) | DAOMAPTAKR1C3AKR1C2 | |
| SCHEMBL28801159 | 0.69 | PARP1 (0.49) | DAOCA12CA9AKR1C3AKR1C2 | |
| SCHEMBL29705824 | 0.69 | PARP1 (0.49) | DAOCA12CA9AKR1C3AKR1C2 | |
| SCHEMBL4238589 | 0.67 | SMN1; SMN2 (0.59) | ALPLALPIPKMMAPTCA1 | |
| SCHEMBL15076650 | 0.67 | PKM (0.46) | ALPLALPIPKMMAPTCA1 | |
| SCHEMBL17824646 | 0.66 | ATIC (0.49) | ALPLALPIPKMMAPTCA1 | |
| SCHEMBL11216223 | 0.66 | POLB (0.61) | ALPLALPIPKMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114965749-B | Detection method of related substances in Shubian bulk drug | 南京海纳医药科技股份有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-114965749-A | Detection method of related substances in sulpiride bulk drug | 南京海纳医药科技股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-114965749-B | Detection method of related substances in Shubian bulk drug | 南京海纳医药科技股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-114965749-A | Detection method of related substances in sulpiride bulk drug | 南京海纳医药科技股份有限公司 | 2022-08-30 | — | — | CN | disclosed |