Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.52 |
| ▸ | MAOB | P27338 | 9/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075377 | 0.77 | CA2 (0.51) | CA1CA2CA12CA4CA5A | |
| SCHEMBL1166873 | 0.74 | DYRK1A (0.58) | MAOAMAOBDYRK1AFTOACHE | |
| SCHEMBL2182261 | 0.73 | LMNA (0.50) | MAOAMAOBCA1CA2CA12 | |
| SCHEMBL29896740 | 0.72 | ALPL (0.49) | CA1CA2CA12CA7ALPL | |
| SCHEMBL365385 | 0.72 | MAOA (0.58) | MAOAMAOBDYRK1AFTOACHE | |
| SCHEMBL3681299 | 0.71 | FTO (0.61) | MAOAMAOBDYRK1AFTOACHE | |
| SCHEMBL1094182 | 0.71 | MAOA (0.59) | MAOAMAOBDYRK1AFTOACHE | |
| SCHEMBL21303291 | 0.71 | MAOA (0.53) | MAOAMAOBDYRK1AFTOACHE | |
| SCHEMBL932337 | 0.71 | MAOA (0.59) | MAOAMAOBDYRK1AFTOACHE | |
| SCHEMBL321544 | 0.71 | MAOA (0.59) | MAOAMAOBDYRK1AFTOACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108218845-A | A kind of chroman -6- sulfonamide ROR gamma modulators and application thereof | 南京柯菲平盛辉制药有限公司 | 2018-06-29 | — | — | CN | disclosed |