Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CPS1 | P31327 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968813 | 1.00 | MAPT (0.57) | MAPTTSHREPHX2RAB9ASLC6A5 | |
| SCHEMBL1447151 | 0.94 | MAPT (0.52) | MAPTTSHREPHX2RAB9ASLC6A5 | |
| SCHEMBL16379735 | 0.88 | MAPT (0.57) | MAPTTSHREPHX2RAB9ASLC6A5 | |
| SCHEMBL5255412 | 0.86 | RAB9A (0.61) | MAPTTSHRRAB9ASLC6A5KMT2A | |
| SCHEMBL30791513 | 0.86 | CCKBR (0.56) | MAPTTSHRRAB9ACNR1KMT2A | |
| SCHEMBL1424241 | 0.86 | CCKBR (0.56) | MAPTTSHRRAB9ACNR1KMT2A | |
| SCHEMBL643698 | 0.86 | CPS1 (0.60) | MAPTRAB9AKMT2ADGAT1NPC1 | |
| SCHEMBL969401 | 0.84 | CCKBR (0.58) | MAPTTSHRRAB9ACNR1KMT2A | |
| SCHEMBL17678114 | 0.83 | MGLL (0.58) | TSHRRAB9AKMT2ANPC1 | |
| SCHEMBL17749695 | 0.83 | HSP90AA1 (0.57) | MAPTTSHRRAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003671-B | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-115003671-A | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2022-09-02 | — | — | CN | disclosed |