SCHEMBL2989889

SCHEMBL2989889

COP(=O)(OC)C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
POLB P06746 1/20 0.53
TSHR P16473 3/20 0.50
ALDH1A1 P00352 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CES1 P23141 5/20 0.44
CES2 O00748 4/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
F2 P00734 1/20 0.43
ELANE P08246 1/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11456405 0.88 MAPT (0.52) LMNAPOLBALDH1A1MEN1KMT2A
SCHEMBL11518818 0.81 LMNA (0.45) LMNAPOLBTSHRALDH1A1MEN1
SCHEMBL11214694 0.81 AKR1C3 (0.60) LMNAALDH1A1MEN1KMT2ANPC1
SCHEMBL788438 0.81 LMNA (0.52) LMNAPOLBTSHRALDH1A1MEN1
SCHEMBL776346 0.81 ALDH1A1 (0.54) LMNAALDH1A1MEN1KMT2ACES1
SCHEMBL13231630 0.79 ALDH1A1 (0.55) LMNAPOLBTSHRALDH1A1CES1
SCHEMBL4851005 0.79 HPGD (0.53) LMNAPOLBTSHRALDH1A1CES1
SCHEMBL4610734 0.79 CES2 (0.57) LMNAALDH1A1MEN1KMT2ACES1
SCHEMBL11411158 0.79 CA1 (0.55) POLBTSHRALDH1A1MEN1KMT2A
SCHEMBL27884622 0.79 LMNA (0.50) LMNAPOLBTSHRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8642676-B2 Polymerizable composition and acrylic resin film MITSUBISHI RAYON CO., LTD. (JP) 2014-02-04 US claimed
EP-3666247-B1 DIVIDED CURABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-12-18 EP disclosed
US-11844847-B2 Sulfur-containing polymerizable monomer and use thereof SUN MEDICAL CO., LTD. (JP) 2023-12-19 US disclosed
CN-112513016-B Sulfur-containing polymerizable monomer and use thereof 尚美德齿科材料有限公司 2023-12-19 CN disclosed
US-11744782-B2 Separately packed curable composition MITSUI CHEMICALS, INC. (JP) 2023-09-05 US disclosed
EP-3658065-B1 MICRO-APPLICATOR FOR USE WITH DENTAL ADHESIVES KULZER & CO GMBH (DE) 2023-07-26 EP disclosed
CN-112940432-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2022-12-30 CN disclosed
CN-115197448-A Spherical powder comprising crosslinked material having polyrotaxane, and method for producing same 株式会社ASM 2022-10-18 CN disclosed
CN-109843986-B Spherical powder comprising crosslinked material having polyrotaxane, and method for producing same 株式会社ASM 2022-08-16 CN disclosed
US-11306160-B2 Curable composition MITSUI CHEMICALS, INC. (JP) 2022-04-19 US disclosed
US-6576725-B1 Iron compound, organomagnesium compound, and alpha-acylphosphonate diester; addition polymerization BRIDGESTONE CORPORATION (JP) 2003-06-10 US disclosed
US-20030073570-A1 Method of preparing oligomers of conjugated dienes with an iron-based catalyst composition BRIDGESTONE CORP. 2003-04-17 US disclosed
US-20030073790-A1 Iron-based catalyst composition for the manufacture of syndiotactic 1, 2-polybutadiene BRIDGESTONE CORP. 2003-04-17 US disclosed
WO-2003018644-A1 IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2003-03-06 WO disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed
EP-0923924-A2 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 1999-06-23 EP disclosed
EP-0473643-B1 PHOTOCURABLE PIGMENTED SECONDARY OPTICAL FIBER COATINGS DSM NV (NL) 1994-12-14 EP disclosed
US-4472577-A CATALYTIC HYDROGENATION OF ALPHA-OXO-PHOSPHONIC ACID ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1984-09-18 US disclosed
EP-0071805-A2 Process for the preparation of alpha-hydroxy-phosphonic-acid esters BAYER AG (DE) 1983-02-16 EP disclosed
EP-0042567-A2 Photopolymerisable mixtures with aroylphosphonic acid esters as photoinitiators BAYER AG (DE) 1981-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11306160-B2 Curable composition COIL, CLPX, CBX7 LMNA 1573/4885POLB 1012/4885TSHR 4794/4885
US-11844847-B2 Sulfur-containing polymerizable monomer and use thereof MGMT, SETDB1, ASH2L LMNA 2881/4885POLB 568/4885TSHR 4059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.