Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.44 |
| ▸ | PRKCG | P05129 | 4/20 | 0.44 |
| ▸ | PRKCB | P05771 | 4/20 | 0.44 |
| ▸ | PRKCA | P17252 | 4/20 | 0.44 |
| ▸ | PRKCH | P24723 | 4/20 | 0.44 |
| ▸ | PRKCI | P41743 | 4/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856332 | 1.00 | KDR (0.51) | KDRCHEK1RAB9ANPC1KDM4E | |
| Aniline SCHEMBL27928992 | 0.91 | RAB9A (0.45) | KDRCHEK1RAB9ANPC1KDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL7811066 | 0.87 | KDR (0.40) | KDRCHEK1RAB9ANPC1KDM4E | |
| Imidazole SCHEMBL5232078 | 0.85 | CYP19A1 (0.40) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL29415921 | 0.79 | PRKD3 (0.62) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL78989 | 0.79 | PRKD3 (0.62) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL3959789 | 0.77 | PRKD3 (0.61) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL5454930 | 0.73 | KDR (0.51) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL1158440 | 0.73 | KDR (0.51) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL31055001 | 0.73 | KDR (0.51) | KDRCHEK1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010715-B | Synthesis method and anticancer activity of 3- (indole-2-yl) succinimide and indolobenzodiazepine compounds | 河南师范大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-115010715-A | Synthesis method and anticancer activity of 3- (indol-2-yl) succinimide and indolophenyldiazepine compounds | 河南师范大学 | 2022-09-06 | — | — | CN | disclosed |