SCHEMBL2990075

SCHEMBL2990075

CC(C)(C)c1cc(OS(=O)(=O)c2ccccc2)cc(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.50
HSD11B1 P28845 1/20 0.49
HSD17B3 P37058 1/20 0.49
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 1/20 0.44
RECQL P46063 1/20 0.44
KMT2A Q03164 1/20 0.44
ENPP1 P22413 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
MAOB P27338 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
GAA P10253 1/20 0.41
MAPK1 P28482 1/20 0.41
CA2 P00918 3/20 0.40
CA12 O43570 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2978101 0.87 ALDH1A1 (0.51) TDP1HSD11B1HSD17B3ALDH1A1MAPT
SCHEMBL2984855 0.85 MEN1 (0.49) HSD11B1HSD17B3ALDH1A1MAPTMEN1
SCHEMBL2986520 0.84 TDP1 (0.61) TDP1HSD11B1HSD17B3ALDH1A1MAPT
Hydrogen Sulfide SCHEMBL15619066 0.83 TDP1 (0.59) TDP1HSD11B1HSD17B3ALDH1A1MAPT
SCHEMBL4622013 0.81 TDP1 (0.64) TDP1ALDH1A1MAPTENPP1SMN1; SMN2
SCHEMBL8393963 0.81 HSD11B1 (0.62) TDP1HSD11B1HSD17B3ALDH1A1MAPT
SCHEMBL8394071 0.80 TDP1 (0.47) TDP1HSD11B1HSD17B3ALDH1A1MAPT
SCHEMBL3838595 0.77 TDP1 (0.61) TDP1HSD11B1HSD17B3ALDH1A1MAPT
SCHEMBL4642756 0.77 TDP1 (0.55) TDP1ALDH1A1MAPTSMN1; SMN2L3MBTL1
Diphenylsulfane SCHEMBL2895786 0.76 MAPT (0.52) TDP1HSD11B1HSD17B3ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101646648-B Tert-butylphenyl sulfonate compound, nonaqueous electrolyte solution for lithium secondary battery using same, and lithium secondary battery using same UBE IND JP 2014-07-16 CN disclosed
US-20140011097-A1 TERT-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME UBE INDUSTRIES, LTD. (JP) 2014-01-09 US disclosed
US-8546599-B2 Tert-butylphenyl sulfonate compound, nonaqueous electrolyte solution for lithium secondary battery using the same, and lithium secondary battery using the same UBE INDUSTRIES, LTD. (JP) 2013-10-01 US disclosed
US-20100055576-A1 tert-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME MU IONIC SOLUTIONS CORPORATION (JP) 2010-03-04 US disclosed
CN-101646648-A Tert-butylphenyl sulfonate compound, nonaqueous electrolyte solution for lithium secondary battery using same, and lithium secondary battery using same UBE IND JP 2010-02-10 CN disclosed
EP-2133327-A1 tert-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME Ube Industries, Ltd. (JP) 2009-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055576-A1 tert-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME TERT, TST, TES TDP1 421/4885HSD11B1 2744/4885HSD17B3 3200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.