Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 10/20 | 0.38 |
| ▸ | LPL | P06858 | 9/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28855398 | 1.00 | LIPG (0.38) | LIPGLPLRXRARXRBRXRG | |
| SCHEMBL5077943 | 0.84 | LPL (0.43) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL15649639 | 0.80 | F11 (0.40) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL15000479 | 0.80 | LIPG (0.45) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL29052780 | 0.79 | LPL (0.34) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL14994064 | 0.78 | FFAR1 (0.39) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL1639345 | 0.78 | ALDH1A1 (0.47) | — | |
| SCHEMBL13468810 | 0.78 | LPL (0.39) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL16419768 | 0.78 | LPL (0.39) | LIPGLPLF11F2PRSS1 | |
| SCHEMBL4430468 | 0.78 | LPL (0.46) | LIPGLPLF11F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110776-A1 | NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2023-01-04 | — | — | EP | disclosed |
| CN-115151538-A | Macrocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-10-04 | — | — | CN | disclosed |