Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17907273 | 1.00 | LMNA (0.59) | LMNANPSR1L3MBTL1AKR1B1NAPRT | |
| Hydrochloric Acid SCHEMBL11510418 | 0.97 | NPSR1 (0.58) | LMNANPSR1L3MBTL1AKR1B1ABCC4 | |
| SCHEMBL11509120 | 0.86 | L3MBTL1 (0.58) | LMNANPSR1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL26414339 | 0.81 | L3MBTL1 (0.52) | LMNANPSR1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL26087979 | 0.81 | NPSR1 (0.56) | LMNANPSR1L3MBTL1HSP90AA1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9539331 | 0.80 | AKR1B1 (0.46) | LMNANPSR1L3MBTL1AKR1B1NAPRT | |
| Hydrochloric Acid SCHEMBL2805432 | 0.79 | NPSR1 (0.71) | LMNANPSR1L3MBTL1NAPRTTSHR | |
| Hydrochloric Acid SCHEMBL6682576 | 0.78 | NPSR1 (0.69) | LMNANPSR1L3MBTL1NAPRTTSHR | |
| Hydrochloric Acid SCHEMBL29676296 | 0.78 | NPSR1 (0.69) | LMNANPSR1L3MBTL1NAPRTTSHR | |
| Hydrochloric Acid SCHEMBL6682577 | 0.78 | NPSR1 (0.69) | LMNANPSR1L3MBTL1NAPRTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022145170-A1 | METHOD AND SYSTEM FOR ELECTROPLATING ARTICLE WITH METAL | ディップソール株式会社 | 2022-07-07 | — | — | WO | disclosed |