Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | FABP2 | P12104 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966853 | 1.00 | UGT2B7 (0.44) | UGT2B7SHBGKDM1AKCNH2KDM1B | |
| SCHEMBL19028362 | 0.83 | UGT2B7 (0.44) | UGT2B7SHBGADRB2CES2CES1 | |
| SCHEMBL8220975 | 0.83 | UGT2B7 (0.44) | UGT2B7SHBGADRB2CES2CES1 | |
| SCHEMBL2850794 | 0.83 | UGT2B7 (0.44) | UGT2B7SHBGADRB2CES2CES1 | |
| SCHEMBL2609188 | 0.83 | LMNA (0.40) | KDM1AKCNH2KDM1BADRB2PTGS1 | |
| SCHEMBL21831869 | 0.81 | KDM1A (0.36) | SHBGKDM1AKCNH2KDM1BIDH1 | |
| SCHEMBL30910946 | 0.81 | KDM1A (0.36) | SHBGKDM1AKCNH2KDM1BIDH1 | |
| SCHEMBL1318569 | 0.80 | CES2 (0.50) | UGT2B7SHBGCES2CES1KMT2A | |
| SCHEMBL11484010 | 0.80 | UGT2B7 (0.48) | UGT2B7KMT2AMEN1LMNAMAPT | |
| SCHEMBL4102499 | 0.80 | CES2 (0.50) | UGT2B7SHBGCES2CES1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-112654621-B | Substituted naphthyridinone compounds useful as T cell activators | 百时美施贵宝公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2022180397-A1 | BENZODIAZEPINES FOR TREATING OR PREVENTING RESPIRATORY SYNCYTIAL VIRUS INFECTION | ReViral Limited (GB) | 2022-09-01 | — | — | WO | disclosed |