Rhamnocitrin

Rhamnocitrin

SCHEMBL29903288

COc1cc(O)c2c(=O)c(O)c(-c3ccc(O)cc3)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 1.00
CYP3A4 P08684 5/20 0.81
KDM4E B2RXH2 4/20 0.81
IP6K2 Q9UHH9 4/20 0.81
MEN1 O00255 3/20 0.81
LMNA P02545 3/20 0.81
MAPT P10636 3/20 0.81
KMT2A Q03164 3/20 0.81
IPMK Q8NFU5 3/20 0.81
APP P05067 2/20 0.81
AKR1B1 P15121 2/20 0.81
HSD17B10 Q99714 2/20 0.81
TDP1 Q9NUW8 2/20 0.81
RECQL P46063 2/20 0.81
THRB P10828 1/20 0.81
ELAVL3 Q14576 1/20 0.81
CYP1A1 P04798 4/20 0.79
CYP1A2 P05177 4/20 0.79
CYP1B1 Q16678 4/20 0.79
ABCB1 P08183 4/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rhamnocitrin SCHEMBL1759429 1.00 MAOA (1.00) MAOACYP3A4KDM4EIP6K2MEN1
SCHEMBL748643 0.95 MAOA (0.90) MAOACYP3A4KDM4EIP6K2MEN1
Izalpinin SCHEMBL29974286 0.91 MAOA (0.83) MAOACYP3A4KDM4EIP6K2MEN1
Izalpinin SCHEMBL7551775 0.91 MAOA (0.83) MAOACYP3A4KDM4EIP6K2MEN1
Rhamnetin SCHEMBL7164573 0.90 MEN1 (1.00) MAOACYP3A4KDM4EIP6K2MEN1
Rhamnetin SCHEMBL29453025 0.90 MEN1 (1.00) MAOACYP3A4KDM4EIP6K2MEN1
Rhamnetin SCHEMBL29496169 0.90 MEN1 (1.00) MAOACYP3A4KDM4EIP6K2MEN1
Rhamnetin SCHEMBL555118 0.90 MEN1 (1.00) MAOACYP3A4KDM4EIP6K2MEN1
Kumatakenin SCHEMBL3351483 0.88 KDM4E (0.83) MAOACYP3A4KDM4EIP6K2MEN1
Kumatakenin SCHEMBL29681818 0.88 KDM4E (0.83) MAOACYP3A4KDM4EIP6K2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113476355-B Plant extraction compound for relieving itching and diminishing inflammation as well as preparation method and application thereof 湖南先伟阳光生物科技有限公司 2022-09-13 CN disclosed