Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.90 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.88 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.88 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.88 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.81 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.81 |
| ▸ | APP | P05067 | 2/20 | 0.81 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | THRB | P10828 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhamnocitrin SCHEMBL29903288 | 0.95 | MAOA (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Rhamnocitrin SCHEMBL1759429 | 0.95 | MAOA (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Kaempferide SCHEMBL29371282 | 0.93 | CYP1A2 (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Kaempferide SCHEMBL426774 | 0.93 | CYP1A2 (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Izalpinin SCHEMBL29974286 | 0.91 | MAOA (0.83) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Izalpinin SCHEMBL7551775 | 0.91 | MAOA (0.83) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Rhamnetin SCHEMBL29496169 | 0.90 | MEN1 (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Rhamnetin SCHEMBL555118 | 0.90 | MEN1 (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Rhamnetin SCHEMBL29453025 | 0.90 | MEN1 (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Rhamnetin SCHEMBL7164573 | 0.90 | MEN1 (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233807-A | Preparation method and quality control method of high-purity kaempferol-7, 4' -dimethyl ether | 广西壮族自治区中医药研究院 | 2020-06-05 | — | — | CN | claimed |
| US-20240115645-A1 | DRUG FOR TREATING UROLITHIASIS-RELATED DISEASE, AND PREPARATION METHOD THEREFOR | HONG ZHANG (CN) | 2024-04-11 | — | — | US | disclosed |
| CN-117723684-A | Cordate houttuynia quality analysis method based on metabonomics | 中山市中智药业集团有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-111233807-B | Preparation method and quality control method of high-purity kaempferol-7, 4' -dimethyl ether | 广西壮族自治区中医药研究院 | 2023-08-11 | — | — | CN | disclosed |
| WO-2022151978-A1 | DRUG FOR TREATING UROLITHIASIS-RELATED DISEASE, AND PREPARATION METHOD THEREFOR | 张弘 | 2022-07-21 | — | — | WO | disclosed |
| CN-108882744-B | Composition containing fructus alpiniae oxyphyllae extract and application of fructus alpiniae oxyphyllae extract | 韩国韩医学研究院 | 2022-04-19 | — | — | CN | disclosed |
| US-20200268827-A1 | COMPOSITION FOR PREVENTION, IMPROVEMENT OR TREATMENT OF OSTEOARTHRITIS COMPRISING ALPINIA OXYPHYLLA EXTRACT AS EFFECTIVE COMPONENT | KOREA INSTITUTE OF ORIENTAL MEDICINE (KR) | 2020-08-27 | — | — | US | disclosed |
| US-10709754-B2 | Composition for preventing, ameliorating, or treating hyperuricemia or metabolic disorders related with hyperuricemia comprising extract of Alpinia oxyphylla as effective ingredient | KOREA INSTITUTE OF ORIENTAL MEDICINE (KR) | 2020-07-14 | — | — | US | disclosed |
| CN-111233807-A | Preparation method and quality control method of high-purity kaempferol-7, 4' -dimethyl ether | 广西壮族自治区中医药研究院 | 2020-06-05 | — | — | CN | disclosed |
| US-20190099465-A1 | COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING HYPERURICEMIA OR METABOLIC DISORDERS RELATED WITH HYPERURICEMIA COMPRISING EXTRACT OF ALPINIA OXYPHYLLA AS EFFECTIVE INGREDIENT | KOREA INSTITUTE OF ORIENTAL MEDICINE (KR) | 2019-04-04 | — | — | US | disclosed |
| US-20110065786-A1 | SYNTHESIS OF ROCAGLAMIDE NATURAL PRODUCTS VIA PHOTOCHEMICAL GENERATION OF OXIDOPYRYLIUM SPECIES | TRUSTEES OF BOSTON UNIVERSITY | 2011-03-17 | — | — | US | disclosed |
| US-7816544-B2 | Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species | TRUSTEES OF BOSTON UNIVERSITY (US) | 2010-10-19 | — | — | US | disclosed |
| US-7816544-B2 | Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species | TRUSTEES OF BOSTON UNIVERSITY (US) | 2010-10-19 | — | — | US | disclosed |
| US-20090299081-A1 | Asymmetric Synthesis of Rocaglamides via Enantioselective Photocycloaddition Mediated by Chiral Bronsted Acids | TRUSTEES OF BOSTON UNIVERSITY (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090299081-A1 | Asymmetric Synthesis of Rocaglamides via Enantioselective Photocycloaddition Mediated by Chiral Bronsted Acids | TRUSTEES OF BOSTON UNIVERSITY (US) | 2009-12-03 | — | — | US | disclosed |
| US-20080177093-A1 | Synthesis of Rocaglamide Natural Products Via Photochemical Generation of Oxidopyrylium Species | TRUSTEES OF BOSTON UNIVERSITY | 2008-07-24 | — | — | US | disclosed |
| US-20080177093-A1 | Synthesis of Rocaglamide Natural Products Via Photochemical Generation of Oxidopyrylium Species | TRUSTEES OF BOSTON UNIVERSITY | 2008-07-24 | — | — | US | disclosed |
| WO-2007139749-A2 | ASYMMETRIC SYNTHESIS OF ROCAGLAMIDES VIA ENANTIOSELECTIVE PHOTOCYCLOADDITION MEDIATED BY CHIRAL BRONSTED ACIDS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-12-06 | — | — | WO | disclosed |
| US-5492911-A | Linsidomine for the treatment for erectile dysfunctions | Stief, Christian (DE) | 1996-02-20 | — | — | US | disclosed |
| WO-1990006104-A1 | USE OF KAEMPFEROL AND CERTAIN DERIVATIVES THEREOF FOR THE PREPARATION OF A COSMETIC OR PHARMACEUTICAL COMPOSITION | LVMH RECHERCHE (FR) | 1990-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299081-A1 | Asymmetric Synthesis of Rocaglamides via Enantioselective Photocycloaddition Mediated by Chiral Bronsted Acids | NFKBIA, NFKB1, NFE2L2 | MAOA 1855/4885CYP1A1 558/4885CYP1A2 617/4885 |
| US-20240115645-A1 | DRUG FOR TREATING UROLITHIASIS-RELATED DISEASE, AND PREPARATION METHOD THEREFOR | HK1, HKDC1, HK2 | MAOA 2130/4885CYP1A1 3173/4885CYP1A2 3504/4885 |
| US-20110065786-A1 | SYNTHESIS OF ROCAGLAMIDE NATURAL PRODUCTS VIA PHOTOCHEMICAL GENERATION OF OXIDOPYRYLIUM SPECIES | NFKBIA, NFE2L2, NFKB1 | MAOA 1402/4885CYP1A1 262/4885CYP1A2 215/4885 |
| US-20080177093-A1 | Synthesis of Rocaglamide Natural Products Via Photochemical Generation of Oxidopyrylium Species | NFKBIA, NFE2L2, NFKB1 | MAOA 1402/4885CYP1A1 262/4885CYP1A2 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.