Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29903448 | 0.86 | KMT2A (0.41) | ALDH1A1CYP2D6CYP2C9CASP1CYP2C19 | |
| SCHEMBL3167072 | 0.86 | KMT2A (0.41) | ALDH1A1CYP2D6CYP2C9CASP1CYP2C19 | |
| SCHEMBL2125795 | 0.81 | KMT2A (0.43) | ALDH1A1CYP2D6CYP2C9CASP1CYP2C19 | |
| SCHEMBL540885 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP2D6CYP2C9CASP1CYP2C19 | |
| SCHEMBL8529530 | 0.81 | KMT2A (0.43) | ALDH1A1CYP2D6CYP2C9CASP1CYP2C19 | |
| SCHEMBL10560805 | 0.80 | KMT2A (0.60) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL28859293 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL10558577 | 0.79 | KMT2A (0.55) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL27873051 | 0.79 | KMT2A (0.41) | ALDH1A1CYP2D6CYP2C9CASP1CYP2C19 | |
| SCHEMBL8601536 | 0.77 | PDE4A (0.41) | ALDH1A1CASP1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596759-A | Base layer, solid positive working resist consisting of two layers with different solubilities, photosensitive component containing aromatic o-nitrocarbinol esters | BASF AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | claimed |
| CN-110914280-B | 6H-thieno [2,3-e ] [1,2,4] triazolo [3,4-c ] [1,2,4] triazab derivatives | 阿尤米制药公司 | 2024-05-03 | — | — | CN | disclosed |
| US-11186588-B2 | 6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,2,4]triazepine derivative | AYUMI PHARMACEUTICAL CORPORATION (JP) | 2021-11-30 | — | — | US | disclosed |
| US-11186588-B2 | 6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,2,4]triazepine derivative | AYUMI PHARMACEUTICAL CORPORATION (JP) | 2021-11-30 | — | — | US | disclosed |
| US-20210130367-A1 | 6H-THIENO[2,3-e][1,2,4]TRIAZOLO[3,4-c][1,2,4]TRIAZEPINE DERIVATIVE | AYUMI PHARMACEUTICAL CORPORATION (JP) | 2021-05-06 | — | — | US | disclosed |
| US-20210130367-A1 | 6H-THIENO[2,3-e][1,2,4]TRIAZOLO[3,4-c][1,2,4]TRIAZEPINE DERIVATIVE | AYUMI PHARMACEUTICAL CORPORATION (JP) | 2021-05-06 | — | — | US | disclosed |
| EP-3640253-A1 | 6H-THIENO[2,3-E][1,2,4]TRIAZOLO[3,4-C][1,2,4]TRIAZEPINE DERIVATIVE | AYUMI Pharmaceutical Corporation (JP) | 2020-04-22 | — | — | EP | disclosed |
| EP-3640253-A1 | 6H-THIENO[2,3-E][1,2,4]TRIAZOLO[3,4-C][1,2,4]TRIAZEPINE DERIVATIVE | AYUMI Pharmaceutical Corporation (JP) | 2020-04-22 | — | — | EP | disclosed |
| CN-110914280-A | 6H-thieno [2,3-e ] [1,2,4] triazolo [3,4-c ] [1,2,4] triaza derivatives | 阿尤米制药公司 | 2020-03-24 | — | — | CN | disclosed |
| US-20180185364-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-07-05 | — | — | US | disclosed |
| US-4565771-A | Production of gravure printing plates having plastic printing layers | BASF AKTIENGESELLSCHAFT (DE) | 1986-01-21 | — | — | US | disclosed |
| EP-0155231-A2 | Image-producing process | CIBA-GEIGY AG (CH) | 1985-09-18 | — | — | EP | disclosed |
| EP-0141389-A2 | Process for the production of image-wise structured resists, and dry resist therefor | BASF Aktiengesellschaft (DE) | 1985-05-15 | — | — | EP | disclosed |
| EP-0134574-A1 | Curable light-sensitive mixture as a positively working recording material | BASF Aktiengesellschaft (DE) | 1985-03-20 | — | — | EP | disclosed |
| EP-0132710-A1 | Light-sensitive recording material for the production of relief or resist patterns | BASF Aktiengesellschaft (DE) | 1985-02-13 | — | — | EP | disclosed |
| US-4465760-A | Production of relief images or resist images by a negative-working method | BASF AKTIENGESELLSCHAFT (DE) | 1984-08-14 | — | — | US | disclosed |
| US-4456679-A | Production of relief images or resist images by a positive-working method | BASF AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | disclosed |
| EP-0101976-A2 | Negative process for obtaining relief or resist patterns | BASF Aktiengesellschaft (DE) | 1984-03-07 | — | — | EP | disclosed |
| EP-0101587-A2 | Positive process for obtaining relief or resist patterns | BASF Aktiengesellschaft (DE) | 1984-02-29 | — | — | EP | disclosed |
| EP-0101586-A2 | Process for the manufacture of plates for intaglio printing using plastic printing foils | BASF Aktiengesellschaft (DE) | 1984-02-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180185364-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | ALDH1A1 3524/4885CYP2D6 3373/4885CYP2C9 3111/4885 |
| US-20210130367-A1 | 6H-THIENO[2,3-e][1,2,4]TRIAZOLO[3,4-c][1,2,4]TRIAZEPINE DERIVATIVE | BRD4, BRD3, BRD2 | ALDH1A1 3279/4885CYP2D6 3024/4885CYP2C9 4140/4885 |
| US-11186588-B2 | 6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,2,4]triazepine derivative | BRD4, BRD3, BRD2 | ALDH1A1 3279/4885CYP2D6 3024/4885CYP2C9 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.